3α(17β)-羟基类固醇脱氢酶 (NAD+)
(重定向自睾酮17β-脱氢酶)
3α(17β)-羟基类固醇脱氢酶 (NAD+)(英语:3α(17β)-Hydroxysteroid dehydrogenase (NAD+),EC 1.1.1.239),原称作睾酮17β-脱氢酶(EC 1.1.1.63),是一种以NAD+或NADP+为受体、作用于供体CH-OH基团上的氧化还原酶。这种酶能催化以下酶促反应:
3α(17β)-羟基类固醇脱氢酶 (NAD+) | |||||||||
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识别码 | |||||||||
EC编号 | 1.1.1.63 | ||||||||
CAS号 | 9028-62-0 | ||||||||
数据库 | |||||||||
IntEnz | IntEnz浏览 | ||||||||
BRENDA | BRENDA入口 | ||||||||
ExPASy | NiceZyme浏览 | ||||||||
KEGG | KEGG入口 | ||||||||
MetaCyc | 代谢路径 | ||||||||
PRIAM | 概述 | ||||||||
PDB | RCSB PDB PDBj PDBe PDBsum | ||||||||
基因本体 | AmiGO / EGO | ||||||||
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参考文献
编辑- ENDAHL GL, KOCHAKIAN CD, HAMM D. Separation of a triphosphopyridine nucleotide-specific from a diphosphopyridine nucleotide-specific 17 beta-hydroxy-(testosterone) dehydrogenase of guinea pig liver. J. Biol. Chem. 1960, 235: 2792–6. PMID 13696735.
- SWEAT ML, SAMUELS LT, LUMRY R. Preparation and characterization of the enzyme which converts testosterone to androstenedione. J. Biol. Chem. 1950, 185 (1): 75–84. PMID 15436478.
- Villee CA and Spencer JM. Some properties of the pyridine nucleotide-specific 17beta-hydroxy steroid dehydrogenase of guinea pig liver. J. Biol. Chem. 1960, 235: 3615–3619. PMID 13781425.