帕吉昔单抗
化合物
帕吉昔单抗（INN：Pagibaximab）是一种嵌合单克隆抗体，用于预防低出生体重婴儿的葡萄球菌败血症。截至2010年3月，该药物尚在进行II/III期临床试验。[1][2]
| 单克隆抗体 | |
|---|---|
| 种类 | 完整抗体 |
| 目标 | 葡萄球菌脂磷壁酸 |
| 临床资料 | |
| ATC码 |
|
| 识别信息 | |
| CAS号 | 595566-61-3  |
| ChemSpider | |
| UNII | |
| 化学信息 | |
| 化学式 | C6462H9996N1728O2028S54 |
| 摩尔质量 | 146,072.36 g·mol−1 |
参考资料
编辑- ^ Weisman LE, Thackray HM, Garcia-Prats JA, Nesin M, Schneider JH, Fretz J, et al. Phase 1/2 double-blind, placebo-controlled, dose escalation, safety, and pharmacokinetic study of pagibaximab (BSYX-A110), an antistaphylococcal monoclonal antibody for the prevention of staphylococcal bloodstream infections, in very-low-birth-weight neonates. Antimicrobial Agents and Chemotherapy. July 2009, 53 (7): 2879–86. PMC 2704668
. PMID 19380597. doi:10.1128/AAC.01565-08.
- ^ Clinical trial number NCT00646399 for "Safety and Efficacy of Pagibaximab Injection in Very Low Birth Weight Neonates for Prevention of Staphylococcal Sepsis" at ClinicalTrials.gov
