M33基因是果蝇属Drosophila多梳家族蛋白哺乳动物基因组中的直系同源[1],在人类基因组中为CBX2基因,在小鼠基因组中为Cbx2,表达的蛋白全长519aa,带有一个克罗莫结构域核定位序列[2]

M33基因在小鼠11号染色体上的位置

参考资料

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  1. ^ Wang G, Horsley D, Ma A, Otte AP, Hutchings A, Butcher GW, Singh PB. M33, a mammalian homologue of Drosophila Polycomb localises to euchromatin within interphase nuclei but is enriched within the centromeric heterochromatin of metaphase chromosomes. Cytogenetics and Cell Genetics. 1997, 78 (1): 50–5. PMID 9345907. doi:10.1159/000134626. 
  2. ^ Hirose S, Komoike Y, Higashinakagawa T. Identification of a nuclear localization signal in mouse polycomb protein, M33. Zoological Science. September 2006, 23 (9): 785–91. PMID 17043400. S2CID 12948692. doi:10.2108/zsj.23.785. 

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