MN9D
細胞系
MN9D细胞是一种小鼠杂交多巴胺能细胞系[1]，由14天龄的C57BL/6J小鼠胚胎的神经元细胞和N18TG2神经母细胞瘤细胞融合而成[2]，能产生多巴胺并表达酪氨酸羟化酶与芳香族L-氨基酸脱羧酶[3]。
参考资料
编辑- ^ Choi, HK; Won, L; Roback, JD; Wainer, BH; Heller, A. Specific modulation of dopamine expression in neuronal hybrid cells by primary cells from different brain regions.. Proceedings of the National Academy of Sciences of the United States of America. 1992-10-01, 89 (19): 8943–7. PMID 1357658. doi:10.1073/pnas.89.19.8943.
- ^ Choi, HK; Won, LA; Kontur, PJ; Hammond, DN; Fox, AP; Wainer, BH; Hoffmann, PC; Heller, A. Immortalization of embryonic mesencephalic dopaminergic neurons by somatic cell fusion.. Brain research. 1991-06-21, 552 (1): 67–76. PMID 1913182. doi:10.1016/0006-8993(91)90661-e.
- ^ Rick, CE; Ebert, A; Virag, T; Bohn, MC; Surmeier, DJ. Differentiated dopaminergic MN9D cells only partially recapitulate the electrophysiological properties of midbrain dopaminergic neurons.. Developmental neuroscience. 2006, 28 (6): 528–37. PMID 17028430. doi:10.1159/000095115.
外部链接
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