奥来鲁单抗
奥来鲁单抗(INN:oleclumab;开发代号:MEDI9447)是一种抗CD73人单克隆抗体,旨在治疗胰腺癌、结直肠癌和其他癌症。[1][2]
单克隆抗体 | |
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种类 | ? |
目标 | NT5E(或叫CD73) |
临床资料 | |
其他名称 | MEDI9447 |
ATC码 |
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识别信息 | |
CAS号 | 1803176-05-7 |
ChemSpider |
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UNII | |
KEGG | |
化学信息 | |
化学式 | C6348H9826N1710O1998S40 |
摩尔质量 | 143,350.81 g·mol−1 |
参考资料
编辑- ^ ClinicalTrial.gov for Oleclumab
- ^ Bendell, Johanna; LoRusso, Patricia; Overman, Michael; Noonan, Anne M.; Kim, Dong-Wan; Strickler, John H.; Kim, Sang-We; Clarke, Stephen; George, Thomas J.; Grimison, Peter S.; Barve, Minal. First-in-human study of oleclumab, a potent, selective anti-CD73 monoclonal antibody, alone or in combination with durvalumab in patients with advanced solid tumors. Cancer immunology, immunotherapy: CII. 2023-07, 72 (7) [2024-06-01]. ISSN 1432-0851. PMID 37016126. doi:10.1007/s00262-023-03430-6. (原始内容存档于2024-06-01).
- ^ Statement On A Nonproprietary Name Adopted By The USAN Council - Oleclumab (页面存档备份,存于互联网档案馆), American Medical Association.