雄二烯酮

化合物
(重定向自雄甾二烯酮

雄二烯酮 (英语:androstadienone), 又称雄甾二烯酮雄甾-4,16,-二烯-3-酮,是人类男性费洛蒙[1],这种化学物质被描述成对人类具有强烈的费洛蒙相关的作用[2][3][4]。雄二烯酮(费洛蒙酮)是雄性荷尔蒙睾固酮代谢物。然而,雄二烯酮并不会产生任何雄性激素或同化激素的活性作用。虽然研究报告显示雄二烯酮会明显地影响异性恋女人与同性恋男人的心情[5],并且很微妙地吸引别人的注意[6],但却不会明显地影响人类的行为。雄二烯酮(费洛蒙酮)目前被添加到香水中,据称能够增加对异性恋女性与同性恋男性的吸引力[7]

雄二烯酮
临床资料
ATC码
  • 未分配
识别信息
  • (8S,9S,10R,13R,14S)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15-decahydrocyclopenta[a]phenanthren-3-one
    OR
    (1S,2R,10S,11S,15R)-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadeca-6,13-dien-5-one
CAS号4075-07-4  checkY
PubChem CID
ChemSpider
UNII
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C19H26O
摩尔质量270.42 g·mol−1
3D模型(JSmol英语JSmol
  • C[C@]12CC[C@H]3[C@H]([C@@H]1CC=C2)CCC4=CC(=O)CC[C@]34C
  • InChI=1S/C19H26O/c1-18-9-3-4-16(18)15-6-5-13-12-14(20)7-11-19(13,2)17(15)8-10-18/h3,9,12,15-17H,4-8,10-11H2,1-2H3/t15-,16-,17-,18-,19-/m0/s1 checkY
  • Key:HNDHDMOSWUAEAW-VMXHOPILSA-N checkY

相关条目

编辑

参见

编辑
  1. ^ 周延鑫. 人類的性費洛蒙 - 國家科學委員會. 科学发展. 2008, 421: 48-53. (原始内容存档于2012-07-24). 
  2. ^ Ivanka Savic,Hans Berglund and Per Lindström. Brain response to putative pheromones in homosexual men. PNAS. 2005, 102 [2011-05-19]. doi:10.1073/pnas.0407998102. (原始内容存档于2021-05-12). 
  3. ^ Robert Sanders University of California Berkeley. Chemical In Male Sweat Increases Cortisol And Sexual Arousal In Heterosexual Women. medical news today. 2007 [2011-05-19]. (原始内容存档于2010-01-11). 
  4. ^ Wyart C, Webster WW, Chen JH, Wilson SR, McClary A, Khan RM, Sobel N. 嗅闻人类男性汗水中的单一成分就会改变女性体内的可体松荷尔蒙 Smelling a single component of male sweat alters levels of cortisol in women. J Neurosci. February 2007, 27 (6): 1261–5. PMID 17287500. doi:10.1523/JNEUROSCI.4430-06.2007. 
  5. ^ Jacob S, McClintock MK. Psychological State and Mood Effects of Steroidal Chemosignals in Women and Men. Hormones and Behavior. 2000, 37: 57-78 [2011-05-19]. PMID 10712859. (原始内容存档于2020-04-08). 
  6. ^ Hummer TA, McClintock MK. Putative human pheromone androstadienone attunes the mind specifically to emotional information. Horm Behav. April 2009, 55 (4): 548–59 [2011-05-18]. PMID 19470369. doi:10.1016/j.yhbeh.2009.01.002. (原始内容存档于2018-02-11). 
  7. ^ Tamsin K. Saxton, Anna Lyndon, Anthony. Littlec and S. Craig Roberts. Evidence that androstadienone, a putative human chemosignal, modulates women’s attributions of men’s attractiveness. Hormones and Behavior. 2008, 54 (5): 597-601 [2022-02-13]. doi:10.1016/j.yhbeh.2008.06.001. (原始内容存档于2011-02-23).