ACY1

ACY1
已知的结构
PDB	直系同源搜索: PDBe RCSB
PDBID列表
	1Q7L
识别号
别名	ACY1；, ACY-1, ACY1D, HEL-S-5, aminoacylase 1
外部ID	OMIM：104620 MGI：87913 HomoloGene：110440 GeneCards：ACY1
相关疾病
	Aminoacylase 1 deficiency
基因位置（人类）
染色体	3号染色体
终止	51,989,197 bp
基因位置（小鼠）
染色体	小鼠9号染色体
终止	106,315,518 bp
RNA表达模式
	查阅更多表达数据
基因本体
分子功能	• 血浆蛋白结合; • 水解酶活性; • metallopeptidase activity; • 金属离子结合; • aminoacylase activity; • 相同蛋白质结合;
细胞组分	• 细胞质; • 细胞质基质; • 外排体;
生物学过程	• xenobiotic metabolic process; • cellular amino acid metabolic process; • 代谢; • 蛋白酶解;
	Sources:Amigo / QuickGO
直系同源
	95
	109652
	ENSG00000243989
	ENSMUSG00000023262
	Q03154
	Q99JW2
	NM_001198898; NM_000666; NM_001198895; NM_001198896; NM_001198897
	NM_001276442; NM_025371
	NP_000657; NP_001185824; NP_001185825; NP_001185826; NP_001185827
	NP_001263371; NP_079647
	维基数据
查看/编辑人类	查看/编辑小鼠

ACY1（氨基酰化酶1，英语：Aminoacylase 1，缩写ACY-1，也称为附睾管腔蛋白-S-5，英语：Epididymis Luminal Protein-S-5，缩写HEL-S-5）是一个人类基因 ACY1 编码的蛋白质，是一种位于胞质溶胶的二聚体锌结合水解酶，EC编号3.5.1.14，位于人类第3号染色体上3p21.1区域。^[6]^[7]^[8]

参考文献

^ 與ACY1相關的疾病；在維基數據上查看/編輯參考.
^ ^2.0 ^2.1 ^2.2 GRCh38: Ensembl release 89: ENSG00000243989 - Ensembl, May 2017
^ ^3.0 ^3.1 ^3.2 GRCm38: Ensembl release 89: ENSMUSG00000023262 - Ensembl, May 2017
^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Miller YE, Drabkin H, Jones C, Fisher JH. Human aminoacylase-1: cloning, regional assignment to distal chromosome 3p21.1, and identification of a cross-hybridizing sequence on chromosome 18. Genomics. Sep 1990, 8 (1): 149–154. PMID 1707030. doi:10.1016/0888-7543(90)90237-O.
^ Voss R, Lerer I, Povey S, Solomon E, Bobrow M. Confirmation and further regional assignment of aminoacylase 1 (acy-1) on human chromosome 3 using a simplified detection method. Annals of Human Genetics. Jul 1980, 44 (Pt 1): 1–9. PMID 6948533. S2CID 21566170. doi:10.1111/j.1469-1809.1980.tb00940.x.
^ Entrez Gene: ACY1 aminoacylase 1.

外部链接

[1] 與ACY1相關的疾病；在維基數據上查看/編輯參考.

[refGRCh38Ensembl-2] 2.0 ^2.1 ^2.2 GRCh38: Ensembl release 89: ENSG00000243989 - Ensembl, May 2017

[refGRCm38Ensembl-3] 3.0 ^3.1 ^3.2 GRCm38: Ensembl release 89: ENSMUSG00000023262 - Ensembl, May 2017

[4] Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[5] Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1707030-6] Miller YE, Drabkin H, Jones C, Fisher JH. Human aminoacylase-1: cloning, regional assignment to distal chromosome 3p21.1, and identification of a cross-hybridizing sequence on chromosome 18. Genomics. Sep 1990, 8 (1): 149–154. PMID 1707030. doi:10.1016/0888-7543(90)90237-O.

[pmid6948533-7] Voss R, Lerer I, Povey S, Solomon E, Bobrow M. Confirmation and further regional assignment of aminoacylase 1 (acy-1) on human chromosome 3 using a simplified detection method. Annals of Human Genetics. Jul 1980, 44 (Pt 1): 1–9. PMID 6948533. S2CID 21566170. doi:10.1111/j.1469-1809.1980.tb00940.x.

[entrez-8] Entrez Gene: ACY1 aminoacylase 1.

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