F4/80

ADGRE1
识别号
别名	ADGRE1；, TM7LN3, EMR1, adhesion G protein-coupled receptor E1
外部ID	OMIM：600493 MGI：106912 HomoloGene：1493 GeneCards：ADGRE1
基因位置（人类）
染色体	19号染色体
终止	6,940,459 bp
基因位置（小鼠）
染色体	小鼠17号染色体
终止	57,790,527 bp
RNA表达模式
	查阅更多表达数据
基因本体
分子功能	• calcium ion binding; • G protein-coupled receptor activity; • transmembrane signaling receptor activity; • signal transducer activity;
细胞组分	• integral component of membrane; • 细胞膜; • integral component of plasma membrane; • 膜; • external side of plasma membrane; • cell periphery; • 胞内;
生物学过程	• G protein-coupled receptor signaling pathway; • cell surface receptor signaling pathway; • 细胞粘附; • adaptive immune response; • 信号转导; • immune system process; • adenylate cyclase-activating G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
直系同源
	2015
	13733
	ENSG00000174837
	ENSMUSG00000004730
	Q14246
	Q61549
	NM_001256252; NM_001256253; NM_001256254; NM_001256255; NM_001974
	NM_010130; NM_001355722; NM_001355723
	NP_001243181; NP_001243182; NP_001243183; NP_001243184; NP_001965
	NP_034260; NP_001342651; NP_001342652
	维基数据
查看/编辑人类	查看/编辑小鼠

F4/80（也称为“含EGF模块黏液素样激素受体1”，EGF-like module-containing mucin-like hormone receptor-like 1，“粘附类G蛋白偶联受体E1”，Adhesion G protein-coupled receptor E1，ADGRE1）是一种细胞表面蛋白质，由人类基因 ADGRE1 编码，属于G蛋白偶联受体B类分泌素受体家族（英语：Secretin receptor family）中粘附类G蛋白偶联受体（英语：Adhesion G protein-coupled receptor）的含EGF模块黏液素样激素受体一员，是人类嗜酸性粒细胞和小鼠巨噬细胞的主要标志物^[5]。

参考文献编辑

^ ^1.0 ^1.1 ^1.2 GRCh38: Ensembl release 89: ENSG00000174837 - Ensembl, May 2017
^ ^2.0 ^2.1 ^2.2 GRCm38: Ensembl release 89: ENSMUSG00000004730 - Ensembl, May 2017
^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Austyn JM, Gordon S. F4/80, a monoclonal antibody directed specifically against the mouse macrophage. European Journal of Immunology. October 1981, 11 (10): 805–15. PMID 7308288. S2CID 8426640. doi:10.1002/eji.1830111013.