LL-100是100种人类淋巴瘤Lymphoma)与白血病Leukemia)细胞系的列表[1],用于药物筛选等许多生物医学研究[2]

细胞系

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Pre-B-ALL

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细胞系 性别 年龄 文献 外部链接
697 12Y [3] CVCL_0079页面存档备份,存于互联网档案馆
KOPN-8 3M [4] CVCL_1866页面存档备份,存于互联网档案馆
NALM-6 19Y [5] CVCL_0092页面存档备份,存于互联网档案馆
REH 15Y [6] CVCL_1650页面存档备份,存于互联网档案馆
SEM 5Y [7] CVCL_0095页面存档备份,存于互联网档案馆
细胞系 性别 年龄 文献 外部链接
BJAB 5Y [8] CVCL_5711页面存档备份,存于互联网档案馆
Daudi 16Y [9] CVCL_0008页面存档备份,存于互联网档案馆
Raji 11Y [10] CVCL_0511页面存档备份,存于互联网档案馆
Ramos 3Y [11] CVCL_0597页面存档备份,存于互联网档案馆
VAL 50Y [12] CVCL_1819页面存档备份,存于互联网档案馆
细胞系 性别 年龄 文献 外部链接
HG-3 70Y [13] CVCL_Y547页面存档备份,存于互联网档案馆
JVM-3 73Y [14] CVCL_1320页面存档备份,存于互联网档案馆
JVM-13 60-69Y [15] CVCL_1318页面存档备份,存于互联网档案馆
MEC-1 61Y [16] CVCL_1870页面存档备份,存于互联网档案馆
PGA-1 未知 [17] CVCL_Y545页面存档备份,存于互联网档案馆

B-NHL: DLBCL ABC

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细胞系 性别 年龄 文献 外部链接
NU-DHL-1 73Y [18] CVCL_1876页面存档备份,存于互联网档案馆
OCI-Ly3 52Y [19] CVCL_8800页面存档备份,存于互联网档案馆
Ri-1 57Y [20] CVCL_1885页面存档备份,存于互联网档案馆
U-2932 29Y [21] CVCL_1896页面存档备份,存于互联网档案馆
U-2946 52Y [22] CVCL_X503[失效链接]

B-NHL: DLBCL GC

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Cell line 性别 年龄 文献 外部链接
DoHH2 60Y [23] CVCL_1179页面存档备份,存于互联网档案馆
OCI-Ly7 48Y [19] CVCL_1881[失效链接]
OCI-Ly19 27Y [24] CVCL_1878页面存档备份,存于互联网档案馆
SU-DHL-4 38Y [25] CVCL_0539页面存档备份,存于互联网档案馆
SU-DHL-6 43Y [25] CVCL_2206页面存档备份,存于互联网档案馆
WSU-DLCL2 41Y [26] CVCL_1902页面存档备份,存于互联网档案馆
细胞系 性别 年龄 文献 外部链接
BONNA-12 46Y [27] CVCL_1090页面存档备份,存于互联网档案馆
Hair-M 86Y [28] CVCL_B401页面存档备份,存于互联网档案馆
HC-1 56Y [29] CVCL_1243页面存档备份,存于互联网档案馆
细胞系 性别 年龄 文献 外部链接
Granta-519 58Y [30] CVCL_1818页面存档备份,存于互联网档案馆
JeKo-1 78Y [31] CVCL_1865页面存档备份,存于互联网档案馆
JVM-2 63Y [14] CVCL_1319页面存档备份,存于互联网档案馆
Mino 68Y [32] CVCL_1872页面存档备份,存于互联网档案馆
REC-1 61Y [33] CVCL_1884页面存档备份,存于互联网档案馆

B-NHL: PEL

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细胞系 性别 年龄 文献 外部链接
BC-3 85Y [34] CVCL_1080页面存档备份,存于互联网档案馆
BCBL-1 40Y [35] CVCL_0165页面存档备份,存于互联网档案馆
CRO-AP2 49Y [36] CVCL_1147页面存档备份,存于互联网档案馆
CRO-AP5 35Y [37] CVCL_1148页面存档备份,存于互联网档案馆

B-NHL: PMBL

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细胞系 性别 年龄 文献 外部链接
U-2940 18Y [38] CVCL_1897页面存档备份,存于互联网档案馆
细胞系 性别 年龄 文献 外部链接
KMS-12-BM 64Y [39] CVCL_1334页面存档备份,存于互联网档案馆
L-363 36Y [40] CVCL_1357页面存档备份,存于互联网档案馆
LP-1 56Y [41] CVCL_0012页面存档备份,存于互联网档案馆
OPM-2 56Y [42] CVCL_1625页面存档备份,存于互联网档案馆
RPMI-8226 61Y [43] CVCL_0014页面存档备份,存于互联网档案馆
U-266 53Y [44] CVCL_0566页面存档备份,存于互联网档案馆
细胞系 性别 年龄 文献 外部链接
HDLM-2 74Y [45] CVCL_0009页面存档备份,存于互联网档案馆
KM-H2 37Y [46] CVCL_1330页面存档备份,存于互联网档案馆
L-428 37Y [45] CVCL_1361页面存档备份,存于互联网档案馆
L-1236 34Y [47] CVCL_2096页面存档备份,存于互联网档案馆
SUP-HD1 37Y [48] CVCL_2208页面存档备份,存于互联网档案馆

T-ALL/T-LL

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细胞系 性别 年龄 文献 外部链接
CCRF-CEM 3Y11M [49] CVCL_0207页面存档备份,存于互联网档案馆
DND-41 13Y [50] CVCL_2022页面存档备份,存于互联网档案馆
HPB-ALL 14Y [51] CVCL_1820页面存档备份,存于互联网档案馆
Jurkat 14Y [52] CVCL_0065页面存档备份,存于互联网档案馆
MOLT-4 19Y [53] CVCL_0013页面存档备份,存于互联网档案馆
RPMI-8402 16Y [54] CVCL_1667页面存档备份,存于互联网档案馆

Mature T-Malignancy

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细胞系 性别 年龄 文献 外部链接
DERL-7 30Y [55] CVCL_2017页面存档备份,存于互联网档案馆
HH 61Y [56] CVCL_1280页面存档备份,存于互联网档案馆
MOTN-1 65Y [57] CVCL_2127页面存档备份,存于互联网档案馆

NK Malignancy

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细胞系 性别 年龄 文献 外部链接
KHYG-1 45Y [58] CVCL_2976页面存档备份,存于互联网档案馆
NK-92 50Y [59] CVCL_2142页面存档备份,存于互联网档案馆
YT 15Y [60] CVCL_1797页面存档备份,存于互联网档案馆
细胞系 性别 年龄 文献 外部链接
DEL 12Y [61] CVCL_1170页面存档备份,存于互联网档案馆
SR-786 11Y [62] CVCL_1711页面存档备份,存于互联网档案馆
SU-DHL-1 10Y [63] CVCL_0538页面存档备份,存于互联网档案馆
SUP-M2 5Y [64] CVCL_2209页面存档备份,存于互联网档案馆

AML myelocytic

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细胞系 性别 年龄 文献 外部链接
EoL-1 33Y [65] CVCL_0258页面存档备份,存于互联网档案馆
HL-60 36Y [66] CVCL_0002页面存档备份,存于互联网档案馆
Kasumi-1 7Y [67] CVCL_0589页面存档备份,存于互联网档案馆
KG-1 59Y [68] CVCL_0374页面存档备份,存于互联网档案馆
NB4 23Y [69] CVCL_0005页面存档备份,存于互联网档案馆
OCI-AML3 57Y [70] CVCL_1844页面存档备份,存于互联网档案馆
SKNO-1 22Y [71] CVCL_2196页面存档备份,存于互联网档案馆

AML monocytic

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细胞系 性别 年龄 文献 外部链接
ME-1 40Y [72] CVCL_2110页面存档备份,存于互联网档案馆
MOLM-13 20Y [73] CVCL_2119页面存档备份,存于互联网档案馆
Mono-Mac-6 64Y [74] CVCL_1426页面存档备份,存于互联网档案馆
MUTZ-3 29Y [75] CVCL_1433页面存档备份,存于互联网档案馆
THP-1 1Y [76] CVCL_0006页面存档备份,存于互联网档案馆
U-937 37Y [77] CVCL_0007页面存档备份,存于互联网档案馆

AML erythroid

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细胞系 性别 年龄 文献 外部链接
F-36P 68Y [78] CVCL_2037页面存档备份,存于互联网档案馆
HEL 30Y [79] CVCL_0001页面存档备份,存于互联网档案馆
OCI-M2 未知 56Y [80] CVCL_2150页面存档备份,存于互联网档案馆
TF-1 35Y [81] CVCL_0559页面存档备份,存于互联网档案馆

AML megakaryocytic

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细胞系 性别 年龄 文献 外部链接
CMK 10M [82][83] CVCL_0216页面存档备份,存于互联网档案馆
ELF-153 41Y [84] CVCL_2031页面存档备份,存于互联网档案馆
M-07e 6M [85] CVCL_2106页面存档备份,存于互联网档案馆
MEGAL 未知 [86] CVCL_1833页面存档备份,存于互联网档案馆
MKPL-1 66Y [87] CVCL_2116页面存档备份,存于互联网档案馆
UT-7 64Y [83] CVCL_2233页面存档备份,存于互联网档案馆

CML myeloid BC

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细胞系 性别 年龄 文献 外部链接
EM-2 5Y [88] CVCL_1196页面存档备份,存于互联网档案馆
K-562 53Y [89][90] CVCL_0004页面存档备份,存于互联网档案馆
KCL-22 32Y [91] CVCL_2091页面存档备份,存于互联网档案馆
Ku812 38Y [92] CVCL_0379页面存档备份,存于互联网档案馆
LAMA-84 29Y [93] CVCL_0388页面存档备份,存于互联网档案馆
MOLM-20 63Y [86] CVCL_2121页面存档备份,存于互联网档案馆

CML lymphoid BC

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细胞系 性别 年龄 文献 外部链接
BV-173 45Y [94] CVCL_0181页面存档备份,存于互联网档案馆
CML-T1 36Y [95] CVCL_1126页面存档备份,存于互联网档案馆
NALM-1 3Y [96] CVCL_0091[失效链接]
TK-6 30Y [97] CVCL_X907页面存档备份,存于互联网档案馆
细胞系 性别 年龄 文献 外部链接
SET-2 71Y [98] CVCL_2187页面存档备份,存于互联网档案馆

另见

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参考文献

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  1. ^ Quentmeier, H; Pommerenke, C; Dirks, WG; Eberth, S; Koeppel, M; MacLeod, RAF; Nagel, S; Steube, K; Uphoff, CC; Drexler, HG. The LL-100 panel: 100 cell lines for blood cancer studies.. Scientific Reports. 3 June 2019, 9 (1): 8218. Bibcode:2019NatSR...9.8218Q. PMC 6547646 . PMID 31160637. doi:10.1038/s41598-019-44491-x. 
  2. ^ Drexler, HG; Quentmeier, H. The LL-100 Cell Lines Panel: Tool for Molecular Leukemia-Lymphoma Research.. International Journal of Molecular Sciences. 13 August 2020, 21 (16): 5800. PMC 7461097 . PMID 32823535. doi:10.3390/ijms21165800 . 
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