NCI-60是美国国家癌症研究所(National Cancer Institute,NCI)列出的60种人类癌症细胞系的列表[1],用于抗癌药物筛选等科学研究[2]

细胞系

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白血病

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细胞系 类型 性别 倍增时间 文献 外部链接
CCRF-CEM 急性淋巴性白血病 26.7h [3] CVCL_0207页面存档备份,存于互联网档案馆
HL-60 急性早幼粒细胞白血病 28.6h [4] CVCL_0002页面存档备份,存于互联网档案馆
K-562 慢性髓细胞性白血病 19.6h [5][6] CVCL_0004页面存档备份,存于互联网档案馆
MOLT-4 急性淋巴性白血病 27.9h [7] CVCL_0013页面存档备份,存于互联网档案馆
RPMI-8226 多发性骨髓瘤 33.5h [8] CVCL_0014页面存档备份,存于互联网档案馆
SR-786 间变性大细胞淋巴瘤英语Anaplastic large-cell lymphoma 28.7h [9] CVCL_1711页面存档备份,存于互联网档案馆

非小细胞肺癌

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细胞系 性别 倍增时间 文献 外部链接
A549 22.9h [10] CVCL_0023页面存档备份,存于互联网档案馆
EKVX 43.6h [11] CVCL_1195页面存档备份,存于互联网档案馆
HOP-62 39h [12] CVCL_1285页面存档备份,存于互联网档案馆
HOP-92 79.5h [13] CVCL_1286页面存档备份,存于互联网档案馆
NCI-H226 61h [14] CVCL_1544页面存档备份,存于互联网档案馆
NCI-H23 33.4h [14] CVCL_1547页面存档备份,存于互联网档案馆
NCI-H322M 35.3h [14] CVCL_1557页面存档备份,存于互联网档案馆
NCI-H460 17.8h [14] CVCL_0459页面存档备份,存于互联网档案馆
NCI-H522 38.2h [14] CVCL_1567页面存档备份,存于互联网档案馆

结直肠癌

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细胞系 性别 倍增时间 文献 外部链接
COLO 205 23.8h [15] CVCL_0218页面存档备份,存于互联网档案馆
HCC2998 未知 31.5h [14] CVCL_1266页面存档备份,存于互联网档案馆
HCT 116 17.4h [16] CVCL_0291页面存档备份,存于互联网档案馆
HCT 15 20.6h [17] CVCL_0292页面存档备份,存于互联网档案馆
HT-29 19.5h [18] CVCL_0320页面存档备份,存于互联网档案馆
KM12 23.7h [13] CVCL_1331页面存档备份,存于互联网档案馆
SW620 20.4h [19] CVCL_0547页面存档备份,存于互联网档案馆

中枢神经系统

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细胞系 性别 倍增时间 文献 外部链接
SF-268 33.1h [20] CVCL_1689页面存档备份,存于互联网档案馆
SF-295 29.5h [14] CVCL_1690页面存档备份,存于互联网档案馆
SF-539 35.4h [14] CVCL_1691页面存档备份,存于互联网档案馆
SNB-19 34.6h [21] CVCL_0535页面存档备份,存于互联网档案馆
SNB-75 62.8h [21] CVCL_1706页面存档备份,存于互联网档案馆
U-251MG 23.8h [22] CVCL_0021页面存档备份,存于互联网档案馆

黑色素瘤

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细胞系 性别 倍增时间 文献 外部链接
LOX-IMVI 20.5h [23] CVCL_1381页面存档备份,存于互联网档案馆
Malme-3M 46.2h [24] CVCL_1438页面存档备份,存于互联网档案馆
M14 26.3h [25] CVCL_1395页面存档备份,存于互联网档案馆
SK-MEL-2 45.5h [26] CVCL_0069页面存档备份,存于互联网档案馆
SK-MEL-28 35.1h [26] CVCL_0526页面存档备份,存于互联网档案馆
SK-MEL-5 25.2h [26] CVCL_0527页面存档备份,存于互联网档案馆
UACC-257 未知 38.5h [13] CVCL_1779页面存档备份,存于互联网档案馆
UACC-62 未知 31.3h [13] CVCL_1780页面存档备份,存于互联网档案馆

卵巢癌

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细胞系 倍增时间 文献 外部链接
IGROV-1 31h [27] CVCL_1304页面存档备份,存于互联网档案馆
OVCAR-3 34.7h [28] CVCL_0465页面存档备份,存于互联网档案馆
OVCAR-4 41.4h [28] CVCL_1627页面存档备份,存于互联网档案馆
OVCAR-5 48.8h [28] CVCL_1628页面存档备份,存于互联网档案馆
OVCAR-8 26.1h [28] CVCL_1629页面存档备份,存于互联网档案馆
SK-OV-3 48.7h [29] CVCL_0532页面存档备份,存于互联网档案馆

肾癌

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细胞系 性别 倍增时间 文献 外部链接
786-O 22.4h [30] CVCL_1051页面存档备份,存于互联网档案馆
A-498 66.8h [31] CVCL_1056页面存档备份,存于互联网档案馆
ACHN 27.5h [32] CVCL_1067页面存档备份,存于互联网档案馆
CAKI-1 39h [33] CVCL_0234页面存档备份,存于互联网档案馆
RXF 393 62.9h [13] CVCL_1673页面存档备份,存于互联网档案馆
SN12C 29.5h [34] CVCL_1705页面存档备份,存于互联网档案馆
TK-10 51.3h [35] CVCL_1773页面存档备份,存于互联网档案馆
UO-31 41.7h [14] CVCL_1911页面存档备份,存于互联网档案馆

前列腺癌

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细胞系 性别 倍增时间 文献 外部链接
PC-3 27.1h [36] CVCL_0035页面存档备份,存于互联网档案馆
DU145 32.3h [37] CVCL_0105页面存档备份,存于互联网档案馆

乳腺癌

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细胞系 类型 倍增时间 文献 外部链接
MCF-7 HR+ 25.4h [38] CVCL_0031页面存档备份,存于互联网档案馆
MDA-MB-231 三阴性乳癌 41.9h [39] CVCL_0062页面存档备份,存于互联网档案馆
MDA-MB-468 三阴性乳癌 62h [40] CVCL_0419页面存档备份,存于互联网档案馆
Hs 578T 三阴性乳癌 53.8h [41] CVCL_0332页面存档备份,存于互联网档案馆
BT-549 三阴性乳癌 53.9h [42] CVCL_1092页面存档备份,存于互联网档案馆
T-47D HR+ 45.5h [43] CVCL_0553页面存档备份,存于互联网档案馆

额外细胞系

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细胞系 类型 来源 文献 外部链接
LXFL 529 非小细胞肺癌 人类 [13] CVCL_D085页面存档备份,存于互联网档案馆
DMS 114 小细胞肺癌 人类男性 [44] CVCL_1174页面存档备份,存于互联网档案馆
SHP-77 小细胞肺癌 人类男性 [45] CVCL_1693页面存档备份,存于互联网档案馆
DLD-1 结直肠癌 人类男性 [46] CVCL_0248页面存档备份,存于互联网档案馆
KM20L2 结直肠癌 人类女性 [47] CVCL_D889页面存档备份,存于互联网档案馆
SNB-78 脑瘤 人类男性 [21] CVCL_B321页面存档备份,存于互联网档案馆
XF 498 脑瘤 人类 [13] CVCL_8928页面存档备份,存于互联网档案馆
RPMI-7951 黑色素瘤 人类女性 [48] CVCL_1666页面存档备份,存于互联网档案馆
M19-MEL 黑色素瘤 人类 [13] CVCL_B415页面存档备份,存于互联网档案馆
RXF-631L 肾癌 人类 [13] CVCL_A780页面存档备份,存于互联网档案馆
SN12K1 肾癌 人类男性 [34] CVCL_D106页面存档备份,存于互联网档案馆
P388 白血病 雌性小鼠 [49] CVCL_7222页面存档备份,存于互联网档案馆
P388/ADR 白血病 雌性小鼠 [14] CVCL_IZ75页面存档备份,存于互联网档案馆

另见

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  • LL-100,100种人类淋巴瘤Lymphoma)与白血病Leukemia)细胞系的列表
  • ICBP43,NCI的“癌症生物学综合计划”(Integrative Cancer Biology Program)列出的43种人类乳腺癌细胞系列表
  • JFCR39,日本癌研究会Japanese Foundation for Cancer Research)列出的39种人类细胞系的列表

参考资料

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