维基百科

NCI-60

NCI-60是美国国家癌症研究所（National Cancer Institute，NCI）列出的60种人类癌症细胞系的列表[1]，用于抗癌药物筛选等科学研究[2]。

细胞系 编辑

白血病 编辑

细胞系 类型 性别 倍增时间 文献 外部链接
CCRF-CEM 急性淋巴性白血病 女 26.7h [3] CVCL_0207
HL-60 急性早幼粒细胞白血病 女 28.6h [4] CVCL_0002
K-562 慢性髓细胞性白血病 女 19.6h [5][6] CVCL_0004
MOLT-4 急性淋巴性白血病 男 27.9h [7] CVCL_0013
RPMI-8226 多发性骨髓瘤 男 33.5h [8] CVCL_0014
SR-786 间变性大细胞淋巴瘤（英语：Anaplastic large-cell lymphoma） 男 28.7h [9] CVCL_1711

非小细胞肺癌 编辑

细胞系 性别 倍增时间 文献 外部链接
A549 男 22.9h [10] CVCL_0023
EKVX 男 43.6h [11] CVCL_1195
HOP-62 女 39h [12] CVCL_1285
HOP-92 男 79.5h [13] CVCL_1286
NCI-H226 男 61h [14] CVCL_1544
NCI-H23 男 33.4h [14] CVCL_1547
NCI-H322M 男 35.3h [14] CVCL_1557
NCI-H460 男 17.8h [14] CVCL_0459
NCI-H522 男 38.2h [14] CVCL_1567

结直肠癌 编辑

细胞系 性别 倍增时间 文献 外部链接
COLO 205 男 23.8h [15] CVCL_0218
HCC2998 未知 31.5h [14] CVCL_1266
HCT 116 男 17.4h [16] CVCL_0291
HCT 15 男 20.6h [17] CVCL_0292
HT-29 女 19.5h [18] CVCL_0320
KM12 男 23.7h [13] CVCL_1331
SW620 男 20.4h [19] CVCL_0547

中枢神经系统 编辑

细胞系 性别 倍增时间 文献 外部链接
SF-268 女 33.1h [20] CVCL_1689
SF-295 女 29.5h [14] CVCL_1690
SF-539 女 35.4h [14] CVCL_1691
SNB-19 男 34.6h [21] CVCL_0535
SNB-75 女 62.8h [21] CVCL_1706
U-251MG 男 23.8h [22] CVCL_0021

黑色素瘤 编辑

细胞系 性别 倍增时间 文献 外部链接
LOX-IMVI 男 20.5h [23] CVCL_1381
Malme-3M 男 46.2h [24] CVCL_1438
M14 男 26.3h [25] CVCL_1395
SK-MEL-2 男 45.5h [26] CVCL_0069
SK-MEL-28 男 35.1h [26] CVCL_0526
SK-MEL-5 女 25.2h [26] CVCL_0527
UACC-257 未知 38.5h [13] CVCL_1779
UACC-62 未知 31.3h [13] CVCL_1780

卵巢癌 编辑

细胞系 倍增时间 文献 外部链接
IGROV-1 31h [27] CVCL_1304
OVCAR-3 34.7h [28] CVCL_0465
OVCAR-4 41.4h [28] CVCL_1627
OVCAR-5 48.8h [28] CVCL_1628
OVCAR-8 26.1h [28] CVCL_1629
SK-OV-3 48.7h [29] CVCL_0532

肾癌 编辑

细胞系 性别 倍增时间 文献 外部链接
786-O 男 22.4h [30] CVCL_1051
A-498 男 66.8h [31] CVCL_1056
ACHN 男 27.5h [32] CVCL_1067
CAKI-1 男 39h [33] CVCL_0234
RXF 393 男 62.9h [13] CVCL_1673
SN12C 男 29.5h [34] CVCL_1705
TK-10 男 51.3h [35] CVCL_1773
UO-31 女 41.7h [14] CVCL_1911

前列腺癌 编辑

细胞系 性别 倍增时间 文献 外部链接
PC-3 男 27.1h [36] CVCL_0035
DU145 男 32.3h [37] CVCL_0105

乳腺癌 编辑

细胞系 类型 倍增时间 文献 外部链接
MCF-7 HR+ 25.4h [38] CVCL_0031
MDA-MB-231 三阴性乳癌 41.9h [39] CVCL_0062
MDA-MB-468 三阴性乳癌 62h [40] CVCL_0419
Hs 578T 三阴性乳癌 53.8h [41] CVCL_0332
BT-549 三阴性乳癌 53.9h [42] CVCL_1092
T-47D HR+ 45.5h [43] CVCL_0553

额外细胞系 编辑

细胞系 类型 来源 文献 外部链接
LXFL 529 非小细胞肺癌 人类 [13] CVCL_D085
DMS 114 小细胞肺癌 人类男性 [44] CVCL_1174
SHP-77 小细胞肺癌 人类男性 [45] CVCL_1693
DLD-1 结直肠癌 人类男性 [46] CVCL_0248
KM20L2 结直肠癌 人类女性 [47] CVCL_D889
SNB-78 脑瘤 人类男性 [21] CVCL_B321
XF 498 脑瘤 人类 [13] CVCL_8928
RPMI-7951 黑色素瘤 人类女性 [48] CVCL_1666
M19-MEL 黑色素瘤 人类 [13] CVCL_B415
RXF-631L 肾癌 人类 [13] CVCL_A780
SN12K1 肾癌 人类男性 [34] CVCL_D106
P388 白血病 雌性小鼠 [49] CVCL_7222
P388/ADR 白血病 雌性小鼠 [14] CVCL_IZ75

另见 编辑

  • LL-100，100种人类淋巴瘤（Lymphoma）与白血病（Leukemia）细胞系的列表
  • ICBP43，NCI的“癌症生物学综合计划”（Integrative Cancer Biology Program）列出的43种人类乳腺癌细胞系列表
  • JFCR39，日本癌研究会（Japanese Foundation for Cancer Research）列出的39种人类细胞系的列表

参考资料 编辑

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取自“https://zh.wikipedia.org/w/index.php?title=NCI-60&oldid=82304362”