模板:已上市安非他命药物中的安非他命物质组成
| 药物 | 化学式 | 分子量[I] | amphetamine base [II] |
amphetamine base in equal doses |
doses with equal base content[III] | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| (g/mol) | (percent) | (30 mg dose) | ||||||||
| total | base | total | dextro- | levo- | dextro- | levo- | ||||
| dextroamphetamine sulfate[2][3] | (C9H13N)2•H2SO4 | |||||||||
| amphetamine sulfate[4] | (C9H13N)2•H2SO4 | |||||||||
| Adderall | ||||||||||
| 25% | dextroamphetamine sulfate[2][3] | (C9H13N)2•H2SO4 | ||||||||
| 25% | amphetamine sulfate[4] | (C9H13N)2•H2SO4 | ||||||||
| 25% | dextroamphetamine saccharate[5] | (C9H13N)2•C6H10O8 | ||||||||
| 25% | amphetamine aspartate monohydrate[6] | (C9H13N)•C4H7NO4•H2O | ||||||||
| lisdexamfetamine dimesylate[7] | C15H25N3O•(CH4O3S)2 | |||||||||
| amphetamine base suspension[IV][8] | C9H13N | |||||||||
参考资料
- ^ Molecular Weight Calculator. Lenntech. [19 August 2015].
- ^ 2.0 2.1 Dextroamphetamine Sulfate USP. Mallinckrodt Pharmaceuticals. March 2014 [19 August 2015].
- ^ 3.0 3.1 D-amphetamine sulfate. Tocris. 2015 [19 August 2015].
- ^ 4.0 4.1 Amphetamine Sulfate USP. Mallinckrodt Pharmaceuticals. March 2014 [19 August 2015].
- ^ Dextroamphetamine Saccharate. Mallinckrodt Pharmaceuticals. March 2014 [19 August 2015].
- ^ Amphetamine Aspartate. Mallinckrodt Pharmaceuticals. March 2014 [19 August 2015].
- ^ Vyvanse Prescribing Information (PDF). United States Food and Drug Administration. Shire US Inc.: 17–21. May 2017 [10 July 2017].
- ^ For uniformity, molecular masses were calculated using the Lenntech Molecular Weight Calculator[1] and were within 0.01g/mol of published pharmaceutical values.
- ^ Amphetamine base percentage=molecular massbase / molecular masstotal. Amphetamine base percentage for Adderall = sum of component percentages / 4.
- ^ (1 / amphetamine base percentage) × scaling factor = (molecular masstotal / molecular massbase) × scaling factor. The values in this column were scaled to a 30 mg dose of dextroamphetamine sulfate. Due to pharmacological differences between these medications (e.g., differences in the release, absorption, conversion, concentration, differing effects of enantiomers, half-life, etc.), the listed values should not be considered equipotent doses.
- ^ This product (Dyanavel XR) is an oral suspension (i.e., a drug that is suspended in a liquid and taken by mouth) that contains 2.5 mg/mL of amphetamine base.[8] The product uses an ion exchange resin to achieve extended release of the amphetamine base.[8]