3-碘-6-甲基喹啉

化合物

3-碘-6-甲基喹啉是一种有机化合物,化学式为C10H8IN。它可由6-甲基喹啉过氧化叔丁醇的反应制得。[3]它和苯乙炔三乙胺存在下、碘化亚铜二氯双(三苯基膦)钯催化下于乙腈中反应,可以得到6-甲基-3-苯乙炔基喹啉。[4]它和二氧化硒加热反应,可以得到3-碘喹啉-6-甲醛。[5]

3-碘-6-甲基喹啉
识别
CAS号 1424246-00-3  checkY
性质
化学式 C10H8IN
摩尔质量 269.08 g·mol−1
外观 白色固体[1]或浅黄色固体[2]
熔点 112-113 °C[1]
106-108 °C[2]
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。

参考文献

编辑
  1. ^ 1.0 1.1 Kai Sun, Yunhe Lv, Junjie Wang, Jingjing Sun, Lulu Liu, Mingyang Jia, Xin Liu, Zhenduo Li, Xin Wang. Regioselective, Molecular Iodine-Mediated C3 Iodination of Quinolines. Organic Letters. 2015-09-18, 17 (18): 4408–4411 [2023-03-04]. ISSN 1523-7060. doi:10.1021/acs.orglett.5b01857. (原始内容存档于2023-03-04) (英语). 
  2. ^ 2.0 2.1 Imran Kazi, Somraj Guha, Govindasamy Sekar. Halogen Bond-Assisted Electron-Catalyzed Atom Economic Iodination of Heteroarenes at Room Temperature. The Journal of Organic Chemistry. 2019-06-07, 84 (11): 6642–6654 [2023-03-04]. ISSN 0022-3263. doi:10.1021/acs.joc.9b00174. (原始内容存档于2023-03-04) (英语). 
  3. ^ Krishna K. Sharma, Dhananjay I. Patel, Rahul Jain. Metal-free synthesis of N-fused heterocyclic iodides via C–H functionalization mediated by tert-butylhydroperoxide. Chemical Communications. 2015, 51 (82): 15129–15132 [2023-03-04]. ISSN 1359-7345. doi:10.1039/C5CC04013B (英语). 
  4. ^ Runfa He, Yang Liu, Yingqi Feng, Lu Chen, Yubing Huang, Feng Xie, Yibiao Li. Access to Thienopyridine and Thienoquinoline Derivatives via Site-Selective C–H Bond Functionalization and Annulation. Organic Letters. 2022-05-06, 24 (17): 3167–3172 [2023-03-04]. ISSN 1523-7060. doi:10.1021/acs.orglett.2c00903. (原始内容存档于2023-03-04) (英语). 
  5. ^ Willms, Lothar; et al. Preparation of nitrogen-containing heterocyclic compounds for plant disease control. 2014 WO 2014048940 A2.