培妥莫單抗

培妥莫單抗
單克隆抗體
種類	?
目標	MUC1
臨床資料
商品名（英語：Drug nomenclature）	Theragyn
給藥途徑	腹膜給藥
ATC碼	未分配;
識別資訊
CAS號	646032-04-4
ChemSpider	none;

培妥莫單抗（INN：pemtumomab；商品名：Theragyn），或譯潘妥莫單抗，是一種用於治療癌症的小鼠單克隆抗體。該藥物通過多態性上皮黏蛋白（PEM或MUC1）對多種類型的癌症（例如卵巢癌和腹膜癌）具有親和力，並將放射性同位素釔-90輸送到腫瘤中。^[1]截至2009年，它正在進行III期臨床試驗。^[2]

它已在歐洲獲得孤兒藥地位。^[3]

參考資料

^ Oei AL, Moreno M, Verheijen RH, Sweep FC, Thomas CM, Massuger LF, von Mensdorff-Pouilly S. Induction of IgG antibodies to MUC1 and survival in patients with epithelial ovarian cancer. International Journal of Cancer. October 2008, 123 (8): 1848–53. PMID 18661524. S2CID 2287723. doi:10.1002/ijc.23725  .
^ Clinical trial number NCT00004115 for "Monoclonal Antibody Therapy in Treating Patients With Ovarian Cancer or Primary Peritoneal Cancer in Remission Following Surgery and Chemotherapy" at ClinicalTrials.gov
^ Antisoma's Lead Product, Pemtumomab Granted European Orphan Drug Status^{[失效連結]}

[1] Oei AL, Moreno M, Verheijen RH, Sweep FC, Thomas CM, Massuger LF, von Mensdorff-Pouilly S. Induction of IgG antibodies to MUC1 and survival in patients with epithelial ovarian cancer. International Journal of Cancer. October 2008, 123 (8): 1848–53. PMID 18661524. S2CID 2287723. doi:10.1002/ijc.23725  .

[2] Clinical trial number NCT00004115 for "Monoclonal Antibody Therapy in Treating Patients With Ovarian Cancer or Primary Peritoneal Cancer in Remission Following Surgery and Chemotherapy" at ClinicalTrials.gov

[3] Antisoma's Lead Product, Pemtumomab Granted European Orphan Drug Status^{[失效連結]}

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