4-溴吡啶

化合物

4-溴吡啶是一種有機化合物,化學式為C5H4BrN。它可由4-氨基吡啶重氮化反應製得。[2]它和2-溴吡啶鋰化後處理為有機鋅試劑)在鈀配合物的催化鋅進行根岸偶聯反應,可以製得2,4'-聯吡啶[3]

4-溴吡啶
識別
CAS號 1120-87-2  checkY
性質
化學式 C5H4BrN
摩爾質量 158 g·mol−1
熔點 6 °C[1]
若非註明,所有數據均出自標準狀態(25 ℃,100 kPa)下。

參考文獻

編輯
  1. ^ Cumper, Charles W. N.; Vogel, Arthur I. 920. Physical properties and chemical constitution. Part XXX. The dipole moments of some halogeno- and cyano-pyridines. Journal of the Chemical Society (Resumed). 1960: 4723. ISSN 0368-1769. doi:10.1039/jr9600004723. 
  2. ^ Murray, Arthur; Langham, Wright H. A Synthesis of Isonicotinic Acid by Halogen—Metal Exchange and Its Application to the Preparation of Isonicotinic-C14Acid Hydrazide1. Journal of the American Chemical Society. 1952, 74 (24): 6289–6290. ISSN 0002-7863. doi:10.1021/ja01144a515. 
  3. ^ Sidler, Daniel R; Barta, Nancy; Li, Wenjie; Hu, Essa; Matty, Louis; Ikemoto, Nori; Campbell, Jeffrey S; Chartrain, Michel; Gbewonyo, Kozo; Boyd, Russell; Corley, Edward G; Ball, Richard G; Larsen, Robert D; Reider, Paul J. Efficient synthesis of the optically active dihydropyrimidinone of a potent α1A- selective adrenoceptor antagonist. Canadian Journal of Chemistry. 2002, 80 (6): 646–652. ISSN 0008-4042. doi:10.1139/v02-079.