英加妥珠單抗
化合物
英加妥珠單抗(INN:imgatuzumab),或譯伊馬曲單抗,是一種人源化單株抗體,設計用於治療癌症。它是一種抗表皮生長因子受體抗體,[1]可作為免疫調節劑。[2][3]
單株抗體 | |
---|---|
種類 | 完整抗體 |
目標 | EGFR |
臨床資料 | |
ATC碼 |
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識別資訊 | |
CAS號 | 959963-46-3 |
ChemSpider |
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UNII | |
KEGG | |
化學資訊 | |
化學式 | C6434H9942N1718O2016S44 |
摩爾質量 | 145,028.96 g·mol−1 |
參考資料
編輯- ^ Kol A, Terwisscha van Scheltinga A, Pool M, Gerdes C, de Vries E, de Jong S. ADCC responses and blocking of EGFR-mediated signaling and cell growth by combining the anti-EGFR antibodies imgatuzumab and cetuximab in NSCLC cells. Oncotarget. July 2017, 8 (28): 45432–45446. PMC 5542198 . PMID 28467975. doi:10.18632/oncotarget.17139.
- ^ World Health Organization. International Nonproprietary Names for Pharmaceutical Substances (INN). Proposed INN: List 107 (PDF). WHO Drug Information. 2012, 26 (2) [2024-03-13]. (原始內容存檔 (PDF)於2016-03-04).
- ^ Statement On A Nonproprietary Name Adopted By The USAN Council - Imgatuzumab (頁面存檔備份,存於互聯網檔案館), American Medical Association.