大麻二酚二甲醚

大麻二酚二甲醚(英语:Cannabidiol dimethyl ether,缩写CBDD)是一种人工合成的大麻二酚衍生物,用于控制动脉粥样硬化中的亚油酸氧化[1][2]

大麻二酚二甲醚
识别信息
  • 1,3-dimethoxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylbenzene
CAS号1242-67-7
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C23H34O2
摩尔质量342.52 g·mol−1
3D模型(JSmol英语JSmol
  • CCCCCC1=CC(=C(C(=C1)OC)[C@@H]2C=C(CC[C@H]2C(=C)C)C)OC
  • InChI=1S/C23H34O2/c1-7-8-9-10-18-14-21(24-5)23(22(15-18)25-6)20-13-17(4)11-12-19(20)16(2)3/h13-15,19-20H,2,7-12H2,1,3-6H3/t19-,20+/m0/s1
  • Key:UYBGHBAVRNATET-VQTJNVASSA-N

参考文献

编辑
  1. ^ Takeda S, Usami N, Yamamoto I, Watanabe K. Cannabidiol-2',6'-dimethyl ether, a cannabidiol derivative, is a highly potent and selective 15-lipoxygenase inhibitor. Drug Metabolism and Disposition. August 2009, 37 (8): 1733–7. PMID 19406952. doi:10.1124/dmd.109.026930. 
  2. ^ Takeda S, Hirayama A, Urata S, Mano N, Fukagawa K, Imamura M, et al. Cannabidiol-2',6'-dimethyl ether as an effective protector of 15-lipoxygenase-mediated low-density lipoprotein oxidation in vitro. Biological & Pharmaceutical Bulletin: 1252–6. PMID 21804214. doi:10.1248/bpb.34.1252 .