甘丙肽受体3
位於22號人類染色體的基因
甘丙肽受体3(英语:Galanin receptor 3,GAL3)是一种由基因GALR3编码的G蛋白偶联受体[1]。
Galanin receptor 3 甘丙肽受体3 | |||
---|---|---|---|
标识 | |||
代号 | GALR3 | ||
扩展标识 | 遗传学:603692 鼠基因:1329003 同源基因:20798 IUPHAR: GAL3 ChEMBL: 2731 GeneCards: GALR3 Gene | ||
RNA表达模式 | |||
更多表达数据 | |||
直系同源体 | |||
物种 | 人类 | 小鼠 | |
Entrez | 8484 | 14429 | |
Ensembl | ENSG00000128310 | ENSMUSG00000006378 | |
UniProt | O60755 | O88853 | |
mRNA序列 | NM_003614 | NM_015738 | |
蛋白序列 | NP_003605 | NP_056553 | |
基因位置 |
Chr 22: 38.22 – 38.22 Mb |
Chr 15: 79.03 – 79.04 Mb | |
PubMed查询 | [1] | [2] | |
另见
编辑参考文献
编辑外部链接
编辑- Galanin Receptors: GAL3. IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. (原始内容存档于2019-10-26).
延伸阅读
编辑- Smith KE, Walker MW, Artymyshyn R; et al. Cloned human and rat galanin GALR3 receptors. Pharmacology and activation of G-protein inwardly rectifying K+ channels. J. Biol. Chem. 1998, 273 (36): 23321–6. PMID 9722565. doi:10.1074/jbc.273.36.23321.
- Kolakowski LF, O'Neill GP, Howard AD; et al. Molecular characterization and expression of cloned human galanin receptors GALR2 and GALR3. J. Neurochem. 1998, 71 (6): 2239–51. PMID 9832121. doi:10.1046/j.1471-4159.1998.71062239.x.
- Iismaa TP, Fathi Z, Hort YJ; et al. Structural organization and chromosomal localization of three human galanin receptor genes. Ann. N. Y. Acad. Sci. 1999, 863: 56–63. PMID 9928159. doi:10.1111/j.1749-6632.1998.tb10683.x.
- Lapsys NM, Furler SM, Henderson NK; et al. A polymorphism in the human GALR3 galanin receptor gene (GALNR3). Mol. Cell. Probes. 1999, 13 (4): 325–7. PMID 10441207. doi:10.1006/mcpr.1999.0254.
- Dunham I, Shimizu N, Roe BA; et al. The DNA sequence of human chromosome 22. Nature. 1999, 402 (6761): 489–95. PMID 10591208. doi:10.1038/990031.
- Berger A, Tuechler C, Almer D; et al. Elevated expression of galanin receptors in childhood neuroblastic tumors. Neuroendocrinology. 2002, 75 (2): 130–8. PMID 11867941. doi:10.1159/000048229.
- Belfer I, Hipp H, Bollettino A; et al. Alcoholism is associated with GALR3 but not two other galanin receptor genes. Genes, Brain and Behavior. 2007, 6 (5): 473–81. PMID 17083333. doi:10.1111/j.1601-183X.2006.00275.x.
- Runesson J, Sollenberg UE, Jurkowski W; et al. Determining receptor–ligand interaction of human galanin receptor type 3. Neurochem. Int. 2010, 57 (7): 804–811. PMID 20817064. doi:10.1016/j.neuint.2010.08.018.
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甘丙肽受体3引用了美国国家医学图书馆提供的资料,这些资料属于公共领域。