白细胞介素-13
白细胞介素-13(英语:Interleukin-13,缩写IL-13)是一种细胞因子,由人类基因 IL13 编码[5][6][7]。IL-13结构上与白细胞介素-4(IL-4)非常相似,有25%的序列相似性[8],都能与由白介素-4受体α亚基(CD124)与白介素-13受体α1(CD213a1)组成的白介素-13受体结合。
参考资料
编辑- ^ 與白細胞介素13相關的疾病;在維基數據上查看/編輯參考.
- ^ 2.0 2.1 2.2 GRCm38: Ensembl release 89: ENSMUSG00000020383 - Ensembl, May 2017
- ^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Minty A, Chalon P, Derocq JM, Dumont X, Guillemot JC, Kaghad M, et al. Interleukin-13 is a new human lymphokine regulating inflammatory and immune responses. Nature. March 1993, 362 (6417): 248–250. Bibcode:1993Natur.362..248M. PMID 8096327. S2CID 4368915. doi:10.1038/362248a0.
- ^ McKenzie AN, Culpepper JA, de Waal Malefyt R, Brière F, Punnonen J, Aversa G, et al. Interleukin 13, a T-cell-derived cytokine that regulates human monocyte and B-cell function. Proceedings of the National Academy of Sciences of the United States of America. April 1993, 90 (8): 3735–3739. Bibcode:1993PNAS...90.3735M. PMC 46376 . PMID 8097324. doi:10.1073/pnas.90.8.3735 .
- ^ Morgan JG, Dolganov GM, Robbins SE, Hinton LM, Lovett M. The selective isolation of novel cDNAs encoded by the regions surrounding the human interleukin 4 and 5 genes. Nucleic Acids Research. October 1992, 20 (19): 5173–5179. PMC 334302 . PMID 1408833. doi:10.1093/nar/20.19.5173.
- ^ Rael EL, Lockey RF. Interleukin-13 signaling and its role in asthma. The World Allergy Organization Journal. March 2011, 4 (3): 54–64. PMC 3651056 . PMID 23283176. doi:10.1097/WOX.0b013e31821188e0.