IL4R
位於16號人類染色體的基因
白介素-4受体α亚基（Interleukin-4 receptor subunit alpha，缩写IL4R-α或IL4R）也称为分化簇124（CD124，cluster of differentiation 124）是一种细胞表面蛋白质，由人类基因 IL4R 编码[5]，与γ链（CD132）共同组成I型白介素-4受体（IL4R type I），或与白介素-13受体α1（CD213a1）组成II型白介素-4受体（IL4R type II），除了结合能白介素-4还能结合白介素-13（IL13）[6]。
| Interleukin-4 receptor alpha chain, N-terminal | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 interleukin-4 / receptor alpha chain complex | |||||||||
| 鉴定 | |||||||||
| 标志 | IL4Ra_N | ||||||||
| Pfam | PF09238（旧版） | ||||||||
| InterPro | IPR015319 | ||||||||
| SCOP | 1iar / SUPFAM | ||||||||
| |||||||||
参考资料
编辑- ^ 1.0 1.1 1.2 GRCh38: Ensembl release 89: ENSG00000077238 - Ensembl, May 2017
- ^ 2.0 2.1 2.2 GRCm38: Ensembl release 89: ENSMUSG00000030748 - Ensembl, May 2017
- ^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Entrez Gene: IL4R interleukin 4 receptor.
- ^ McCormick SM, Heller NM. Commentary: IL-4 and IL-13 receptors and signaling. Cytokine. September 2015, 75 (1): 38–50. PMC 4546937
. PMID 26187331. doi:10.1016/j.cyto.2015.05.023.
外部链接
编辑- 医学主题词表（MeSH）：CD124+Antigen
- PDBe-KB provides an overview of all the structure information available in the PDB for Human Interleukin-4 receptor subunit alpha