血小板内皮细胞黏附分子

血小板内皮细胞黏附分子(英语:Platelet endothelial cell adhesion molecule,缩写PECAM-1,也称为CD31,cluster of differentiation 31,分化簇31)是一种细胞表面蛋白质,由人类17号染色体上的基因 PECAM1 编码,是内皮细胞CFU-GM细胞的主要标志物[5][6][7]

PECAM1
已知的结构
PDB直系同源搜索: PDBe RCSB
识别号
别名PECAM1;, CD31, CD31/EndoCAM, GPIIA', PECA1, PECAM-1, endoCAM, platelet and endothelial cell adhesion molecule 1, PCAM-1
外部IDOMIM173445 MGI97537 HomoloGene47925 GeneCardsPECAM1
基因位置(人类
17号染色体
染色体17号染色体[1]
17号染色体
PECAM1的基因位置
PECAM1的基因位置
基因座17q23.3起始64,319,415 bp[1]
终止64,413,776 bp[1]
RNA表达模式




查阅更多表达数据
直系同源
物种人类小鼠
Entrez
Ensembl
UniProt
mRNA​序列

NM_000442

NM_001032378
​NM_008816
​NM_001305157
​NM_001305158

蛋白序列

NP_000433

NP_001027550
​NP_001292086
​NP_001292087
​NP_032842

基因位置​(UCSC)Chr 17: 64.32 – 64.41 MbChr 11: 106.55 – 106.64 Mb
PubMed​查找[3][4]
维基数据
查看/编辑人类查看/编辑小鼠

参考文献

编辑
  1. ^ 1.0 1.1 1.2 GRCh38: Ensembl release 89: ENSG00000261371 - Ensembl, May 2017
  2. ^ 2.0 2.1 2.2 GRCm38: Ensembl release 89: ENSMUSG00000020717 - Ensembl, May 2017
  3. ^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine. 
  4. ^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine. 
  5. ^ Newman PJ, Berndt MC, Gorski J, White GC, Lyman S, Paddock C, Muller WA. PECAM-1 (CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily. Science. March 1990, 247 (4947): 1219–1222. Bibcode:1990Sci...247.1219N. PMID 1690453. doi:10.1126/science.1690453. 
  6. ^ Gumina RJ, Kirschbaum NE, Rao PN, vanTuinen P, Newman PJ. The human PECAM1 gene maps to 17q23. Genomics. June 1996, 34 (2): 229–232. PMID 8661055. doi:10.1006/geno.1996.0272. 
  7. ^ Xie Y, Muller WA. Fluorescence in situ hybridization mapping of the mouse platelet endothelial cell adhesion molecule-1 (PECAM1) to mouse chromosome 6, region F3-G1. Genomics. October 1996, 37 (2): 226–228. PMID 8921400. doi:10.1006/geno.1996.0546. 

外部链接

编辑