17α-甲基雌二醇

化合物

17α-甲基雌二醇(英语:17α-Methylestradiol,缩写17α-Me-E2,商品名有Ginecosid、Ginecoside、Mediol和Renodiol)是一种雌激素类药物,可用于治疗更年期综合症[2][3][4][1]

17α-甲基雌二醇
临床资料
商品名英语Drug nomenclatureGinecosid, Ginecoside, Mediol, Renodiol
其他名称NSC-52245; 17α-Methylestradiol; 17α-ME; 17α-Methylestra-1,3,5(10)-triene-3,17β-diol
给药途径By mouth[1]
药物类别英语Drug classEstrogen
识别信息
  • (8R,9S,13S,14S,17S)-13,17-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
CAS号302-76-1  checkY
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
ECHA InfoCard100.005.572 编辑维基数据链接
化学信息
化学式C19H26O2
摩尔质量286.42 g·mol−1
3D模型(JSmol英语JSmol
  • CC12CCC3C(C1CCC2(C)O)CCC4=C3C=CC(=C4)O
  • InChI=1S/C19H26O2/c1-18-9-7-15-14-6-4-13(20)11-12(14)3-5-16(15)17(18)8-10-19(18,2)21/h4,6,11,15-17,20-21H,3,5,7-10H2,1-2H3/t15-,16-,17+,18+,19+/m1/s1
  • Key:JXQJDYXWHSVOEF-GFEQUFNTSA-N

另见

编辑

参考文献

编辑
  1. ^ 1.0 1.1 HEGEMANN O. [Oral hormonal treatment with methylestrene-olone & methylestradiol as early pregnancy tests]. Medizinische. May 1959, 4 (21): 1032–3. PMID 13673847 (德语). 
  2. ^ J. Elks. The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. 14 November 2014: 898– [2021-06-27]. ISBN 978-1-4757-2085-3. (原始内容存档于2021-04-18). 
  3. ^ Drugs.com. Methylestradiol. [2 January 2016]. (原始内容存档于2017-09-26). 
  4. ^ IARC Working Group on the Evaluation of Carcinogenic Risks to Humans; World Health Organization; International Agency for Research on Cancer. Combined Estrogen-progestogen Contraceptives and Combined Estrogen-progestogen Menopausal Therapy. World Health Organization. 2007: 389– [2021-06-27]. ISBN 978-92-832-1291-1. (原始内容存档于2021-07-05).