HU-345是一种有机化合物,分子式C21H24O3,属于一种人工合成的HU大麻素,与其它大麻素相比,HU-345带有的结构,能抑制人工血管接环中发生的血管新生[1][2]

HU-345
识别信息
  • 6,6,9-Trimethyl-3-pentyl-1H-benzo[c]chromene-1,4(6H)-dione
PubChem CID
ChemSpider
ChEMBL
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C21H24O3
摩尔质量324.42 g·mol−1
3D模型(JSmol英语JSmol
  • O=C2\C(=C/C(=O)C=3c1c(ccc(c1)C)C(OC2=3)(C)C)CCCCC
  • InChI=1S/C21H24O3/c1-5-6-7-8-14-12-17(22)18-15-11-13(2)9-10-16(15)21(3,4)24-20(18)19(14)23/h9-12H,5-8H2,1-4H3 checkY
  • Key:UFDYTRQMIXJHTH-UHFFFAOYSA-N checkY

参考文献

编辑
  1. ^ Kogan NM, Blázquez C, Alvarez L, Gallily R, Schlesinger M, Guzmán M, Mechoulam R. A cannabinoid quinone inhibits angiogenesis by targeting vascular endothelial cells. Molecular Pharmacology. July 2006, 70 (1): 51–59. PMID 16571653. S2CID 4830577. doi:10.1124/mol.105.021089. 
  2. ^ US granted 0092584,Mechoulam R, Kogan NM, Rabinowitz R, Schlesinger M,“Therapeutic Use of Quinonoid Derivatives of Cannabinoids”,发表于2011-04-21,发行于2011-04-21