SNAPC1

位於14號人類染色體的基因

snRNA激活蛋白复合体第一亚基(英语:snRNA-activating protein complex subunit 1)是一个由人类基因SNAPC1编码的蛋白质[1][2]

小核RNA激活蛋白复合体,多肽1,43千道尔顿
Small nuclear RNA activating complex, polypeptide 1, 43kDa
标识
代号 SNAPC1; PTFgamma; SNAP43
扩展标识 遗传学600591 鼠基因1922877 同源基因2317 GeneCards: SNAPC1 Gene
RNA表达模式
更多表达数据
直系同源体
物种 人类 小鼠
Entrez 6617 75627
Ensembl ENSG00000023608 ENSMUSG00000021113
UniProt Q16533 Q8K0S9
mRNA序列 NM_003082 NM_178392
蛋白序列 NP_003073 NP_848479
基因位置 Chr 14:
62.23 – 62.26 Mb
Chr 12:
73.96 – 73.98 Mb
PubMed查询 [1] [2]

相互作用

编辑

SNAPC1能与SNAPC4[3]SNAPC3[3][4]视网膜母细胞瘤蛋白[5]发生相互作用

参考文献

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  1. ^ Maeng JH, Yoon JB. The human PTFgamma/SNAP43 gene: structure, chromosomal location, and identification of a VNTR in 5'-UTR. J Biochem. September 1998, 124 (1): 23–7. PMID 9644240. 
  2. ^ Entrez Gene: SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa. 
  3. ^ 3.0 3.1 Ma, B; Hernandez N. A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc. J. Biol. Chem. (United States). February 2001, 276 (7): 5027–35. ISSN 0021-9258. PMID 11056176. doi:10.1074/jbc.M009301200. 
  4. ^ Henry, R W; Ma B, Sadowski C L, Kobayashi R, Hernandez N. Cloning and characterization of SNAP50, a subunit of the snRNA-activating protein complex SNAPc. EMBO J. (ENGLAND). Dec 1996, 15 (24): 7129–36. ISSN 0261-4189. PMC 452539 . PMID 9003788. 
  5. ^ Hirsch, H A; Gu L, Henry R W. The Retinoblastoma Tumor Suppressor Protein Targets Distinct General Transcription Factors To Regulate RNA Polymerase III Gene Expression. Mol. Cell. Biol. (UNITED STATES). Dec 2000, 20 (24): 9182–91. ISSN 0270-7306. PMC 102176 . PMID 11094070. doi:10.1128/MCB.20.24.9182-9191.2000. 

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