模板:PBB/2194

Fatty acid synthase 脂肪酸合酶
PDB rendering based on 1xkt.
有效结构 PDB 直系同源检索：PDBe, RCSB PDB查询代码列表 1XKT, 2CG5, 2JFD, 2JFK, 2PX6, 3HHD, 3TJM
标识
代号	FASN; FAS; OA-519; SDR27X1
扩展标识	遗传学：600212 鼠基因：95485 同源基因：55800 ChEMBL: 4158 GeneCards: FASN Gene
EC编号	1.1.1.100
基因本体论描述 分子功能 · nucleotide binding · fatty acid synthase activity · [acyl-carrier-protein S-acetyltransferase activity] · [acyl-carrier-protein S-malonyltransferase activity] · 3-oxoacyl-[acyl-carrier-protein synthase activity] · 3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity] · 3-hydroxypalmitoyl-[acyl-carrier-protein dehydratase activity] · enoyl-[acyl-carrier-protein reductase (NADPH, B-specific) activity] · oleoyl-[acyl-carrier-protein hydrolase activity] · protein binding · zinc ion binding · myristoyl-[acyl-carrier-protein hydrolase activity] · palmitoyl-[acyl-carrier-protein hydrolase activity] · 3-hydroxyoctanoyl-[acyl-carrier-protein dehydratase activity] 细胞成分 · cytoplasm · mitochondrion · Golgi apparatus · cytosol · plasma membrane · melanosome · glycogen granule 生物过程 · energy reserve metabolic process · fatty acid metabolic process · fatty acid biosynthetic process · vitamin metabolic process · water-soluble vitamin metabolic process · pantothenate metabolic process · triglyceride biosynthetic process · positive regulation of cellular metabolic process · long-chain fatty-acyl-CoA biosynthetic process · cellular lipid metabolic process · small molecule metabolic process Sources: Amigo / QuickGO
RNA表达模式
更多表达数据
直系同源体
物种	人类	小鼠
Entrez	2194	14104
Ensembl	ENSG00000169710	ENSMUSG00000025153
UniProt	P49327	P19096
mRNA序列	NM_004104.4	NM_007988.3
蛋白序列	NP_004095.4	NP_032014.3
基因位置	Chr 17: 80.04 – 80.06 Mb	Chr 11: 120.81 – 120.82 Mb
PubMed查询	[1]	[2]