Kallikrein-related peptidase 3
Crystallographic structure of human prostate-specific antigen (green/gold cartoon) covalently attached to an substrate acyl intermediate (multicolor sticks, carbon = white, nitrogen = blue, oxygen = red) and an glucosaminemanose disaccharide (spheres, carbon = yellow and oxygen = red).[1]
有效结构
PDB 直系同源检索:PDBe, RCSB
标识
代号 KLK3; APS; KLK2A1; PSA; hK3
扩展标识 遗传学176820 鼠基因892021 同源基因68141 ChEMBL: 2099 GeneCards: KLK3 Gene
EC编号 3.4.21.77
RNA表达模式
更多表达数据
直系同源体
物种 人类 小鼠
Entrez 354 13646
Ensembl ENSG00000142515 ENSMUSG00000060177
UniProt P07288 P15948
mRNA序列 NM_001030047.1 NM_010114.1
蛋白序列 NP_001025218.1 NP_034244.1
基因位置 Chr 19:
51.36 – 51.36 Mb
Chr 7:
44.11 – 44.12 Mb
PubMed查询 [1] [2]

参考资料

  1. ^ PDB 2ZCK; Ménez R, Michel S, Muller BH, Bossus M, Ducancel F, Jolivet-Reynaud C, Stura EA. Crystal structure of a ternary complex between human prostate-specific antigen, its substrate acyl intermediate and an activating antibody. J. Mol. Biol. February 2008, 376 (4): 1021–33. PMID 18187150. doi:10.1016/j.jmb.2007.11.052.