CDKN2C

位於1號人類染色體的基因

CDKN2C,全称周期蛋白依赖性激酶4抑制蛋白C(英语:Cyclin-dependent kinase 4 inhibitor C),也称为p18蛋白,由人类基因 CDKN2C编码,是周期蛋白依赖性激酶抑制蛋白INK4家族的一员[5][6][7]

CDKN2C
已知的结构
PDB直系同源搜索: PDBe RCSB
识别号
别名CDKN2C;, INK4C, p18, p18-INK4C, cyclin-dependent kinase inhibitor 2C, cyclin dependent kinase inhibitor 2C
外部IDOMIM603369 MGI105388 HomoloGene966 GeneCardsCDKN2C
基因位置(人类
1号染色体
染色体1号染色体[1]
1号染色体
CDKN2C的基因位置
CDKN2C的基因位置
基因座1p32.3起始50,960,745 bp[1]
终止50,974,634 bp[1]
RNA表达模式


查阅更多表达数据
直系同源
物种人类小鼠
Entrez
Ensembl
UniProt
mRNA​序列

NM_078626
​NM_001262

NM_001301368
​NM_007671

蛋白序列

NP_001253
​NP_523240

NP_001288297
​NP_031697

基因位置​(UCSC)Chr 1: 50.96 – 50.97 MbChr 4: 109.52 – 109.52 Mb
PubMed​查找[3][4]
维基数据
查看/编辑人类查看/编辑小鼠

参考文献

编辑
  1. ^ 1.0 1.1 1.2 GRCh38: Ensembl release 89: ENSG00000123080 - Ensembl, May 2017
  2. ^ 2.0 2.1 2.2 GRCm38: Ensembl release 89: ENSMUSG00000028551 - Ensembl, May 2017
  3. ^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine. 
  4. ^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine. 
  5. ^ Guan, K L; Jenkins, C W; Li, Y; Nichols, M A; Wu, X; O'Keefe, C L; Matera, A G; Xiong, Y. Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function.. Genes & Development. 1994-12-15, 8 (24). ISSN 0890-9369. doi:10.1101/gad.8.24.2939 (英语). 
  6. ^ Blais, Alexandre; Labrie, Yvan; Pouliot, Frédéric; Lachance, Yves; Labrie, Claude. Structure of the Gene Encoding the Human Cyclin-Dependent Kinase Inhibitor p18 and Mutational Analysis in Breast Cancer. Biochemical and Biophysical Research Communications. 1998-06-09, 247 (1). ISSN 0006-291X. doi:10.1006/bbrc.1998.8497 (英语). 
  7. ^ Entrez Gene: CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4). [2021-08-23]. (原始内容存档于2010-12-05). 

外部链接

编辑