TAS2R42
位於12號人類染色體的基因
味觉感受器，类型2，成员42，TAS2R42 是一个人类基因组中TAS2R42基因编码的蛋白质，是苦味味觉感受器的一员。[1][2]
| 味觉感受器，类型2，成员42 | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 标识 | |||||||||||||
| 代号 | TAS2R42; T2R24; T2R55; TAS2R55; hT2R55 | ||||||||||||
| 扩展标识 | 遗传学：613966 鼠基因：2681280 同源基因：52298 IUPHAR: GeneCards: TAS2R42 Gene | ||||||||||||
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| 直系同源体 | |||||||||||||
| 物种 | 人类 | 小鼠 | |||||||||||
| Entrez | 353164 | 387356 | |||||||||||
| Ensembl | ENSG00000186136 | ENSMUSG00000057699 | |||||||||||
| UniProt | Q7RTR8 | Q7M708 | |||||||||||
| mRNA序列 | NM_181429 | NM_207030 | |||||||||||
| 蛋白序列 | NP_852094 | NP_996913 | |||||||||||
| 基因位置 |
Chr 12: 11.34 – 11.34 Mb |
Chr 6: 132.96 – 132.96 Mb | |||||||||||
| PubMed查询 | [1] | [2] | |||||||||||
另见
编辑参考文献
编辑- ^ Entrez Gene: taste receptor.
- ^ Shi P, Zhang J, Yang H, Zhang YP. Adaptive diversification of bitter taste receptor genes in Mammalian evolution. Mol. Biol. Evol. May 2003, 20 (5): 805–14. PMID 12679530. doi:10.1093/molbev/msg083.
拓展阅读
编辑- Fischer A, Gilad Y, Man O, Pääbo S. Evolution of bitter taste receptors in humans and apes.. Mol. Biol. Evol. 2005, 22 (3): 432–6. PMID 15496549. doi:10.1093/molbev/msi027.
- Strausberg RL, Feingold EA, Grouse LH; et al. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.. Proc. Natl. Acad. Sci. U.S.A. 2002, 99 (26): 16899–903. PMC 139241
. PMID 12477932. doi:10.1073/pnas.242603899. - Go Y, Satta Y, Takenaka O, Takahata N. Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.. Genetics. 2005, 170 (1): 313–26. PMC 1449719 . PMID 15744053. doi:10.1534/genetics.104.037523.
- Scherer SE, Muzny DM, Buhay CJ; et al. The finished DNA sequence of human chromosome 12.. Nature. 2006, 440 (7082): 346–51. PMID 16541075. doi:10.1038/nature04569.
