雄烷二醇
化合物
雄烷二醇（英语：Androstanediol，通常指的是3α-雄烷二醇，缩写3α-diol，全称5α-雄烷-3α,17β-二醇，5α-androstane-3α,17β-diol）是一种内源性的弱雄激素，也是双氢睾酮（DHT）的主要代谢产物[1][2][3]。
| 雄烷二醇 | |
|---|---|
| |
| IUPAC名 (3R,5S,8R,9S,10S,13S,14S,17S)-10,13-Dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol | |
| 系统名 (1S,2S,5R,7S,10R,11S,14S,15S)-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadecane-5,14-diol (1S,2S,5R,7S,10R,11S,14S,15S)-2,15-二甲基四环[8.7.0.02,7.011,15]-5,14-十七烷二醇 | |
| 别名 | Hombreol |
| 识别 | |
| CAS号 | 1852-53-5 
|
| PubChem | 15818 |
| ChemSpider | 15039 |
| SMILES |
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| InChI |
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| InChIKey | CBMYJHIOYJEBSB-KHOSGYARBM |
| 性质 | |
| 化学式 | C19H32O2 |
| 摩尔质量 | 292.46 g·mol−1 |
| 若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。 | |
另见
编辑参考文献
编辑- ^ Reddy DS. Neurosteroids: endogenous role in the human brain and therapeutic potentials. Progress in Brain Research 186. 2010: 113–37. ISBN 9780444536303. PMC 3139029
. PMID 21094889. doi:10.1016/B978-0-444-53630-3.00008-7. |journal=被忽略 (帮助) - ^ Jin Y, Penning TM. Steroid 5alpha-reductases and 3alpha-hydroxysteroid dehydrogenases: key enzymes in androgen metabolism. Best Pract. Res. Clin. Endocrinol. Metab. March 2001, 15 (1): 79–94. PMID 11469812. doi:10.1053/beem.2001.0120.
- ^ Penning TM, Bauman DR, Jin Y, Rizner TL. Identification of the molecular switch that regulates access of 5alpha-DHT to the androgen receptor. Mol. Cell. Endocrinol. February 2007,. 265-266: 77–82. PMC 1857325 . PMID 17223255. doi:10.1016/j.mce.2006.12.007.
