Ro67-4853
化合物
Ro67-4853是一种含氮有机化合物，化学式为C19H19NO4，作为代谢型谷氨酸受体的mGluR1亚型的别构调节剂用于科学研究。[1][2][3]
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| 识别信息 | |
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| CAS号 | 302841-89-0 |
| PubChem CID | |
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| CompTox Dashboard (EPA) | |
| 化学信息 | |
| 化学式 | C19H19NO4 |
| 摩尔质量 | 325.36 g·mol−1 |
| 3D模型（JSmol） | |
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参考文献
编辑- ^ Knoflach F, Mutel V, Jolidon S, Kew JN, Malherbe P, Vieira E, Wichmann J, Kemp JA. Positive allosteric modulators of metabotropic glutamate 1 receptor: characterization, mechanism of action, and binding site. Proceedings of the National Academy of Sciences of the United States of America. November 2001, 98 (23): 13402–7. Bibcode:2001PNAS...9813402K. PMC 60883
. PMID 11606768. doi:10.1073/pnas.231358298 .
- ^ Hemstapat K, de Paulis T, Chen Y, Brady AE, Grover VK, Alagille D, Tamagnan GD, Conn PJ. A novel class of positive allosteric modulators of metabotropic glutamate receptor subtype 1 interact with a site distinct from that of negative allosteric modulators (PDF). Molecular Pharmacology. August 2006, 70 (2): 616–626. PMID 16645124. S2CID 2719603. doi:10.1124/mol.105.021857. （原始内容 (PDF)存档于2019-02-22）.
- ^ Sheffler DJ, Conn PJ. Allosteric potentiators of metabotropic glutamate receptor subtype 1a differentially modulate independent signaling pathways in baby hamster kidney cells. Neuropharmacology. September 2008, 55 (4): 419–27. PMC 2600811 . PMID 18625258. doi:10.1016/j.neuropharm.2008.06.047.
