JWH-073
化合物
此條目可參照英語維基百科相應條目來擴充。 (2024年1月29日) |
JWH-073,化學名N-正丁基-3-(1-萘甲酰基)吲哚,分子式C23H21NO,屬於萘甲酰基吲哚類JWH系列大麻素,是大麻素受體CB1和CB2的全激動劑[3],由約翰·威廉·霍夫曼小組合成[4]。
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法律規範狀態 | |
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識別資訊 | |
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CAS號 | 208987-48-8 ![]() |
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CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.230.192 |
化學資訊 | |
化學式 | C23H21NO |
摩爾質量 | 327.43 g·mol−1 |
3D模型(JSmol) | |
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參考文獻
編輯- ^ Grozījumi Ministru kabineta 2005.gada 8.novembra noteikumos Nr.847 "Noteikumi par Latvijā kontrolējamajām narkotiskajām vielām, psihotropajām vielām un prekursoriem". Legal Acts of the Republic of Latvia. [2024-01-29]. (原始內容存檔於2010-09-14) (Latvian).
- ^ Anvisa. RDC Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial [Collegiate Board Resolution No. 804 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control]. Diário Oficial da União. 2023-07-24 (2023-07-25) [2023-08-27]. (原始內容存檔於2023-08-27) (巴西葡萄牙語).
- ^ Lisa K. Brents, Anna Gallus-Zawada, Anna Radominska-Pandya, Tamara Vasiljevik, Thomas E Prisinzano, William E Fantegrossi, Jeffery H Moran, Paul L Prather. Monohydroxylated metabolites of the K2 synthetic cannabinoid JWH-073 retain intermediate to high cannabinoid 1 receptor (CB1R) affinity and exhibit neutral antagonist to partial agonist activity. Biochemical Pharmacology. 2012, 83 (7): 952–961 [2024-01-29]. PMID 22266354. doi:10.1016/j.bcp.2012.01.004. hdl:1808/22684 . (原始內容存檔於2023-10-31).
JWH-073 displays equivalent efficacy to that of the CB1R full agonist CP-55,940
- ^ Aung MM, Griffin G, Huffman JW, Wu M, Keel C, Yang B, Showalter VM, Abood ME, Martin BR. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2)receptor binding. Drug Alcohol Depend. August 2000, 60 (2): 133–40. PMID 10940540. doi:10.1016/S0376-8716(99)00152-0.