CSF2RB

CSF2RB
已知的結構
PDB	直系同源搜尋: PDBe RCSB
PDBID列表
	1C8P、1EGJ、1GH7、2GYS、4NKQ、5DWU、2NA9、2NA8
識別號
別名	CSF2RB；, CD131, CDw131, IL3RB, IL5RB, SMDP5, colony stimulating factor 2 receptor beta common subunit, betaGMR, colony stimulating factor 2 receptor subunit beta
外部ID	OMIM：138981 MGI：1339759 HomoloGene：339 GeneCards：CSF2RB
基因位置（人類）
染色體	22號染色體
終止	36,940,439 bp
基因位置（小鼠）
染色體	小鼠15號染色體
終止	78,238,047 bp
基因本體
分子功能	• interleukin-3 receptor activity; • interleukin-5 receptor activity; • 血漿蛋白結合; • cytokine receptor activity; • protein tyrosine kinase activity; • signaling receptor activity;
細胞組分	• integral component of membrane; • 膜; • 細胞膜; • integral component of plasma membrane; • granulocyte macrophage colony-stimulating factor receptor complex; • 胞內;
生物學過程	• respiratory gaseous exchange by respiratory system; • MAPK cascade; • 信號轉導; • response to lipopolysaccharide; • peptidyl-tyrosine phosphorylation; • interleukin-5-mediated signaling pathway; • cellular response to interleukin-3; • interleukin-3-mediated signaling pathway; • cytokine-mediated signaling pathway;
	Sources:Amigo / QuickGO
直系同源
	1439
	12983
	ENSG00000100368
	ENSMUSG00000071713
	P32927
	P26955
	NM_000395
	NM_007780; NM_001358854
	NP_000386
	NP_031806; NP_001345783
	維基數據
檢視/編輯人類	檢視/編輯小鼠

CSF2RB又稱為CD131（cluster of differentiation 131），是以下I型細胞因子受體的共用亞基：

參考文獻

^ ^1.0 ^1.1 ^1.2 GRCh38: Ensembl release 89: ENSG00000100368 - Ensembl, May 2017
^ ^2.0 ^2.1 ^2.2 GRCm38: Ensembl release 89: ENSMUSG00000071713 - Ensembl, May 2017
^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Woodcock et al., Three residues in the common beta chain of the human GM-CSF, IL-3 and IL-5 receptors are essential for GM-CSF and IL-5 but not IL-3 high affinity binding and interact with Glu21 of GM-CSF. EMBO J. 1994 November 1; 13(21): 5176–5185.

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