PTENP1

磷酸酯酶與張力蛋白同源物，假基因1，簡稱為PTENP1，是人類常在多種腫瘤中發生突變的一種基因。

磷酸酯酶與張力蛋白同源物1
標識
代號	PTENP1; PTEN-rs; PTEN2; PTENpg1; PTH2; psiPTEN
擴展標識	遺傳學：613531 GeneCards: PTENP1 Gene
基因本體論描述 分子功能 · protein tyrosine/serine/threonine phosphatase activity · hydrolase activity 生物過程 · protein amino acid dephosphorylation
直系同源體
物種	人類	小鼠
Entrez	11191	n/a
Ensembl	ENSG00000237984	n/a
UniProt	n/a	n/a
mRNA序列	NR_023917	n/a
蛋白序列	n/a	n/a
基因位置	Chr 9: 33.67 – 33.68 Mb	n/a
PubMed查詢	[1]	n/a

深入閱讀

• Kong D; Suzuki A; Zou TT; et al. PTEN1 is frequently mutated in primary endometrial carcinomas. Nat. Genet. 1997, 17 (2): 143–4. PMID 9326929. doi:10.1038/ng1097-143. 
• Teng DH; Hu R; Lin H; et al. MMAC1/PTEN mutations in primary tumor specimens and tumor cell lines. Cancer Res. 1998, 57 (23): 5221–5. PMID 9393738. 
• Sakurada A; Suzuki A; Sato M; et al. Infrequent genetic alterations of the PTEN/MMAC1 gene in Japanese patients with primary cancers of the breast, lung, pancreas, kidney, and ovary. Jpn. J. Cancer Res. 1998, 88 (11): 1025–8. PMID 9439675. 
• Kim SK; Su LK; Oh Y; et al. Alterations of PTEN/MMAC1, a candidate tumor suppressor gene, and its homologue, PTH2, in small cell lung cancer cell lines. Oncogene. 1998, 16 (1): 89–93. PMID 9467947. doi:10.1038/sj.onc.1201512. 
• Dahia PL; FitzGerald MG; Zhang X; et al. A highly conserved processed PTEN pseudogene is located on chromosome band 9p21. Oncogene. 1998, 16 (18): 2403–6. PMID 9620558. doi:10.1038/sj.onc.1201762. 
• Forgacs E; Biesterveld EJ; Sekido Y; et al. Mutation analysis of the PTEN/MMAC1 gene in lung cancer. Oncogene. 1998, 17 (12): 1557–65. PMID 9794233. doi:10.1038/sj.onc.1202070. 
• Fujii GH, Morimoto AM, Berson AE, Bolen JB. Transcriptional analysis of the PTEN/MMAC1 pseudogene, psiPTEN. Oncogene. 1999, 18 (9): 1765–9. PMID 10208437. doi:10.1038/sj.onc.1202492. 
• Trojan J; Plotz G; Brieger A; et al. Activation of a cryptic splice site of PTEN and loss of heterozygosity in benign skin lesions in Cowden disease. J. Invest. Dermatol. 2002, 117 (6): 1650–3. PMID 11886535. doi:10.1046/j.0022-202x.2001.01954.x. 
• Strausberg RL; Feingold EA; Grouse LH; et al. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. 2003, 99 (26): 16899–903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.