帕扎克兰
化合物
帕扎克兰（INN：Pozanicline；开发代号：ABT-089）是一种含氮有机化合物，分子式C11H16N2O，是美国雅培公司研发的益智药和神经保护药。[1][2][3]
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| 识别信息 | |
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| CAS号 | 161417-03-4  |
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| 化学信息 | |
| 化学式 | C11H16N2O |
| 摩尔质量 | 192.26 g·mol−1 |
| 3D模型（JSmol） | |
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参考文献
编辑- ^ Lin NH, Gunn DE, Ryther KB, Garvey DS, Donnelly-Roberts DL, Decker MW, et al. Structure-activity studies on 2-methyl-3-(2(S)-pyrrolidinylmethoxy) pyridine (ABT-089): an orally bioavailable 3-pyridyl ether nicotinic acetylcholine receptor ligand with cognition-enhancing properties. Journal of Medicinal Chemistry. January 1997, 40 (3): 385–90. PMID 9022806. doi:10.1021/jm960233u.
- ^ Sullivan JP, Donnelly-Roberts D, Briggs CA, Anderson DJ, Gopalakrishnan M, Xue IC, et al. ABT-089 [2-methyl-3-(2-(S)-pyrrolidinylmethoxy)pyridine]: I. A potent and selective cholinergic channel modulator with neuroprotective properties. The Journal of Pharmacology and Experimental Therapeutics. October 1997, 283 (1): 235–46. PMID 9336329.
- ^ Decker MW, Bannon AW, Curzon P, Gunther KL, Brioni JD, Holladay MW, et al. ABT-089 [2-methyl-3-(2-(S)-pyrrolidinylmethoxy)pyridine dihydrochloride]: II. A novel cholinergic channel modulator with effects on cognitive performance in rats and monkeys. The Journal of Pharmacology and Experimental Therapeutics. October 1997, 283 (1): 247–58. PMID 9336330.