海绵骨针

骨针（英语：spicules）是多数海绵（多孔动物门）经生物矿化产生的构造，提供结构支持与防御的功能^[1]。四大类群的海绵中有三者（寻常海绵纲、六放海绵纲与同骨海绵纲）的骨针成分为非晶质的硅^[2]，钙质海绵纲的骨针成分则为碳酸钙^[3]。骨针的大小与形状因海绵种类不同而异，常作为分类依据^[4]。

形成

海绵骨针的生成过程^[4]
（A）海绵骨针于中质层（英语：Mesohyl）合成： AI：造骨细胞内轴丝（AF）形成；AII：骨针成长；AIII：两细胞生成的骨针相互连接；AIV：成熟骨针在海绵中转移位置
（B）海绵死亡、组织分解
（C）脱落的海绵组织
（D）脱落的骨针

骨针是由海绵中质层（英语：Mesohyl）的造骨细胞（英语：Sclerocyte）合成^[5]^[6]，受基因调控^[7]。此类细胞中可生成蛋白质组成的轴丝^[8]，为骨针的轴心结构，随后于其上生成硅或碳酸钙等矿物，轴丝的大小与形状将决定骨针的形状^[9]。

参考文献

^ Jones, Adam C.; Blum, James E.; Pawlik, Joseph R. Testing for defensive synergy in Caribbean sponges: Bad taste or glass spicules?. Journal of Experimental Marine Biology and Ecology. 2005-08-08, 322 (1): 67–81. ISSN 0022-0981. S2CID 85614908. doi:10.1016/j.jembe.2005.02.009.
^ Hooper, John N. A.; Van Soest, Rob W. M. Systema Porifera. A Guide to the Classification of Sponges. Systema Porifera. 2002: 1–7. ISBN 978-0-306-47260-2. doi:10.1007/978-1-4615-0747-5_1.
^ Rossi, Andre L.; Campos, Andrea P.C.; Barroso, Madalena M.S.; Klautau, Michelle; Archanjo, Bráulio S.; Borojevic, Radovan; Farina, Marcos; Werckmann, Jacques. Long-range crystalline order in spicules from the calcareous sponge Paraleucilla magna (Porifera, Calcarea). Acta Biomaterialia. 2014, 10 (9): 3875–3884. PMID 24487057. doi:10.1016/j.actbio.2014.01.023.
^ ^4.0 ^4.1 Łukowiak, Magdalena. Utilizing sponge spicules in taxonomic, ecological and environmental reconstructions: A review. PeerJ. 2020, 8: e10601. PMC 7751429  . PMID 33384908. doi:10.7717/peerj.10601.
^ Custódio, Márcio; Hajdu, Eduardo; Muricy, Guilherme. In vivo study of microsclere formation in sponges of the genus Mycale (Demospongiae, Poecilosclerida). Zoomorphology. 2002, 121 (4): 203–211. S2CID 39893025. doi:10.1007/s00435-002-0057-9.
^ Müller, Werner E. G.; Rothenberger, Matthias; Boreiko, Alexandra; Tremel, Wolfgang; Reiber, Andreas; Schröder, Heinz C. Formation of siliceous spicules in the marine demosponge Suberites domuncula. Cell and Tissue Research. 2005, 321 (2): 285–297. PMID 15947968. S2CID 12720013. doi:10.1007/s00441-005-1141-5.
^ Krasko, Anatoli; Lorenz, Bernd; Batel, Renato; Schröder, Heinz C.; Müller, Isabel M.; Müller, Werner E. G. Expression of silicatein and collagen genes in the marine sponge Suberites domuncula is controlled by silicate and myotrophin. European Journal of Biochemistry. 2000, 267 (15): 4878–4887. PMID 10903523. doi:10.1046/j.1432-1327.2000.01547.x.
^ Shimizu, K.; Cha, J.; Stucky, G. D.; Morse, D. E. Silicatein : Cathepsin L-like protein in sponge biosilica. Proceedings of the National Academy of Sciences. 1998, 95 (11): 6234–6238. PMC 27641  . PMID 9600948. doi:10.1073/pnas.95.11.6234  .
^ Pisera, Andrzej. Some aspects of silica deposition in lithistid demosponge desmas. Microscopy Research and Technique. 2003, 62 (4): 312–326. PMID 14534905. S2CID 26495972. doi:10.1002/jemt.10398.

[1] Jones, Adam C.; Blum, James E.; Pawlik, Joseph R. Testing for defensive synergy in Caribbean sponges: Bad taste or glass spicules?. Journal of Experimental Marine Biology and Ecology. 2005-08-08, 322 (1): 67–81. ISSN 0022-0981. S2CID 85614908. doi:10.1016/j.jembe.2005.02.009.

[Hooper2002-2] Hooper, John N. A.; Van Soest, Rob W. M. Systema Porifera. A Guide to the Classification of Sponges. Systema Porifera. 2002: 1–7. ISBN 978-0-306-47260-2. doi:10.1007/978-1-4615-0747-5_1.

[3] Rossi, Andre L.; Campos, Andrea P.C.; Barroso, Madalena M.S.; Klautau, Michelle; Archanjo, Bráulio S.; Borojevic, Radovan; Farina, Marcos; Werckmann, Jacques. Long-range crystalline order in spicules from the calcareous sponge Paraleucilla magna (Porifera, Calcarea). Acta Biomaterialia. 2014, 10 (9): 3875–3884. PMID 24487057. doi:10.1016/j.actbio.2014.01.023.

[Łukowiak2020-4] 4.0 ^4.1 Łukowiak, Magdalena. Utilizing sponge spicules in taxonomic, ecological and environmental reconstructions: A review. PeerJ. 2020, 8: e10601. PMC 7751429  . PMID 33384908. doi:10.7717/peerj.10601.

[5] Custódio, Márcio; Hajdu, Eduardo; Muricy, Guilherme. In vivo study of microsclere formation in sponges of the genus Mycale (Demospongiae, Poecilosclerida). Zoomorphology. 2002, 121 (4): 203–211. S2CID 39893025. doi:10.1007/s00435-002-0057-9.

[6] Müller, Werner E. G.; Rothenberger, Matthias; Boreiko, Alexandra; Tremel, Wolfgang; Reiber, Andreas; Schröder, Heinz C. Formation of siliceous spicules in the marine demosponge Suberites domuncula. Cell and Tissue Research. 2005, 321 (2): 285–297. PMID 15947968. S2CID 12720013. doi:10.1007/s00441-005-1141-5.

[7] Krasko, Anatoli; Lorenz, Bernd; Batel, Renato; Schröder, Heinz C.; Müller, Isabel M.; Müller, Werner E. G. Expression of silicatein and collagen genes in the marine sponge Suberites domuncula is controlled by silicate and myotrophin. European Journal of Biochemistry. 2000, 267 (15): 4878–4887. PMID 10903523. doi:10.1046/j.1432-1327.2000.01547.x.

[8] Shimizu, K.; Cha, J.; Stucky, G. D.; Morse, D. E. Silicatein : Cathepsin L-like protein in sponge biosilica. Proceedings of the National Academy of Sciences. 1998, 95 (11): 6234–6238. PMC 27641  . PMID 9600948. doi:10.1073/pnas.95.11.6234  .

[Pisera2003-9] Pisera, Andrzej. Some aspects of silica deposition in lithistid demosponge desmas. Microscopy Research and Technique. 2003, 62 (4): 312–326. PMID 14534905. S2CID 26495972. doi:10.1002/jemt.10398.

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