1,16-二溴十六烷

1,16-二溴十六烷
英文名	1,16-dibromohexadecane
别名	1,16-二溴代十六烷
识别
CAS号	45223-18-5
SMILES	BrCCCCCCCCCCCCCCCCBr;
性质
化学式	C16H32Br2
摩尔质量	384.23 g·mol−1
熔点	53.5—55 °C（326.6—328.1 K）; 57—58 °C（330—331 K）
	若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。

1,16-二溴十六烷是一种有机溴化合物，化学式为C₁₆H₃₂Br₂。1,16-二溴十六烷可由NBS（或四溴化碳^[3]）和1,16-十六烷二醇在三苯基膦的存在下反应制得。^[4]它和碘化钠在丙酮中回流，可以得到1,16-二碘十六烷；^[5]它和氰化钠在二甲基亚砜中加热反应，得到1,18-十八烷二腈。^[6]

参考文献

^ R.G. Woolford. THE ELECTROLYSIS OF ω-BROMOCARBOXYLIC ACIDS. Canadian Journal of Chemistry. 1962-09-01, 40 (9): 1846–1850 [2020-11-16]. ISSN 0008-4042. doi:10.1139/v62-280 （英语）.
^ Alexander K.L. Yuen, Falk Heinroth, Antony J. Ward, Anthony F. Masters, Thomas Maschmeyer. Novel bis(methylimidazolium)alkane bolaamphiphiles as templates for supermicroporous and mesoporous silicas. Microporous and Mesoporous Materials. 2012-01, 148 (1): 62–72 [2020-11-16]. doi:10.1016/j.micromeso.2011.06.036. （原始内容存档于2018-06-11）（英语）.
^ Jaejun Lee, Vivian M. Lau, Yi Ren, Christopher M. Evans, Jeffrey S. Moore, Nancy R. Sottos. Effect of Polymerized Ionic Liquid Structure and Morphology on Shockwave Energy Dissipation. ACS Macro Letters. 2019-04-26: 535–539 [2020-11-16]. ISSN 2161-1653. doi:10.1021/acsmacrolett.9b00133. （原始内容存档于2019-06-07）（英语）.
^ Blanka E. Janicek, Joshua G. Hinman, Jordan J. Hinman, Sang hyun Bae, Meng Wu, Jacob Turner, Huei-Huei Chang, Eugene Park, Rachel Lawless, Kenneth S. Suslick, Catherine J. Murphy, Pinshane Y. Huang. Quantitative Imaging of Organic Ligand Density on Anisotropic Inorganic Nanocrystals. Nano Letters. 2019-09-11, 19 (9): 6308–6314 [2020-11-16]. ISSN 1530-6984. doi:10.1021/acs.nanolett.9b02434. （原始内容存档于2020-10-06）（英语）.
^ Javier Castilla, Rocío Rísquez, Katsumi Higaki, Eiji Nanba, Kousaku Ohno, Yoshiyuki Suzuki, Yolanda Díaz, Carmen Ortiz Mellet, José M. García Fernández, Sergio Castillón. Conformationally-locked N-glycosides: Exploiting long-range non-glycone interactions in the design of pharmacological chaperones for Gaucher disease. European Journal of Medicinal Chemistry. 2015-01, 90: 258–266 [2020-11-16]. doi:10.1016/j.ejmech.2014.11.002. （原始内容存档于2020-09-23）（英语）.
^ Michèle Calas, Mahama Ouattara, Gilles Piquet, Zyta Ziora, Y. Bordat, Marie L. Ancelin, Roger Escale, Henri Vial. Potent Antimalarial Activity of 2-Aminopyridinium Salts, Amidines, and Guanidines. Journal of Medicinal Chemistry. 2007-12, 50 (25): 6307–6315 [2020-11-16]. ISSN 0022-2623. doi:10.1021/jm0704752 （英语）.

[1] R.G. Woolford. THE ELECTROLYSIS OF ω-BROMOCARBOXYLIC ACIDS. Canadian Journal of Chemistry. 1962-09-01, 40 (9): 1846–1850 [2020-11-16]. ISSN 0008-4042. doi:10.1139/v62-280 （英语）.

[2] Alexander K.L. Yuen, Falk Heinroth, Antony J. Ward, Anthony F. Masters, Thomas Maschmeyer. Novel bis(methylimidazolium)alkane bolaamphiphiles as templates for supermicroporous and mesoporous silicas. Microporous and Mesoporous Materials. 2012-01, 148 (1): 62–72 [2020-11-16]. doi:10.1016/j.micromeso.2011.06.036. （原始内容存档于2018-06-11）（英语）.

[3] Jaejun Lee, Vivian M. Lau, Yi Ren, Christopher M. Evans, Jeffrey S. Moore, Nancy R. Sottos. Effect of Polymerized Ionic Liquid Structure and Morphology on Shockwave Energy Dissipation. ACS Macro Letters. 2019-04-26: 535–539 [2020-11-16]. ISSN 2161-1653. doi:10.1021/acsmacrolett.9b00133. （原始内容存档于2019-06-07）（英语）.

[4] Blanka E. Janicek, Joshua G. Hinman, Jordan J. Hinman, Sang hyun Bae, Meng Wu, Jacob Turner, Huei-Huei Chang, Eugene Park, Rachel Lawless, Kenneth S. Suslick, Catherine J. Murphy, Pinshane Y. Huang. Quantitative Imaging of Organic Ligand Density on Anisotropic Inorganic Nanocrystals. Nano Letters. 2019-09-11, 19 (9): 6308–6314 [2020-11-16]. ISSN 1530-6984. doi:10.1021/acs.nanolett.9b02434. （原始内容存档于2020-10-06）（英语）.

[5] Javier Castilla, Rocío Rísquez, Katsumi Higaki, Eiji Nanba, Kousaku Ohno, Yoshiyuki Suzuki, Yolanda Díaz, Carmen Ortiz Mellet, José M. García Fernández, Sergio Castillón. Conformationally-locked N-glycosides: Exploiting long-range non-glycone interactions in the design of pharmacological chaperones for Gaucher disease. European Journal of Medicinal Chemistry. 2015-01, 90: 258–266 [2020-11-16]. doi:10.1016/j.ejmech.2014.11.002. （原始内容存档于2020-09-23）（英语）.

[6] Michèle Calas, Mahama Ouattara, Gilles Piquet, Zyta Ziora, Y. Bordat, Marie L. Ancelin, Roger Escale, Henri Vial. Potent Antimalarial Activity of 2-Aminopyridinium Salts, Amidines, and Guanidines. Journal of Medicinal Chemistry. 2007-12, 50 (25): 6307–6315 [2020-11-16]. ISSN 0022-2623. doi:10.1021/jm0704752 （英语）.

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