2,3-二氨基丙酸
2,3-二氨基丙酸（Dpr）[1]是一种非蛋白氨基酸，出现于一些次级代谢产物，包括双效菌素A[2]和结核放线菌素。[3]
| l-2,3-二氨基丙酸 | |
|---|---|
| |
| IUPAC名 3-Amino-L-alanine 3-氨基-L-丙氨酸 | |
| 系统名 (2S)-2,3-Diaminopropanoic acid | |
| 识别 | |
| CAS号 | 4033-39-0 |
| PubChem | 97328 |
| ChemSpider | 87849 |
| SMILES |
|
| ChEBI | 16303 |
| KEGG | C03401 |
| 性质 | |
| 化学式 | C3H8N2O2 |
| 摩尔质量 | 104.11 g·mol−1 |
| 若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。 | |
生物合成
编辑2,3-二氨基丙酸根离子由丝氨酸的磷酸吡哆醛（PLP）介导胺化生成。
参考文献
编辑- ^ Frenkel-Pinter M, Haynes JW, C M, Petrov AS, Burcar BT, Krishnamurthy R, et al. Selective incorporation of proteinaceous over nonproteinaceous cationic amino acids in model prebiotic oligomerization reactions. Proceedings of the National Academy of Sciences of the United States of America. August 2019, 116 (33): 16338–16346. PMC 6697887
. PMID 31358633. doi:10.1073/pnas.1904849116 .
- ^ Rogers EW, Molinski TF. Asymmetric synthesis of diastereomeric diaminoheptanetetraols. A proposal for the configuration of (+)-zwittermicin a. Organic Letters. February 2007, 9 (3): 437–40. PMC 2729442 . PMID 17249781. doi:10.1021/ol062804a.
- ^ Thomas MG, Chan YA, Ozanick SG. Deciphering tuberactinomycin biosynthesis: isolation, sequencing, and annotation of the viomycin biosynthetic gene cluster. Antimicrobial Agents and Chemotherapy. September 2003, 47 (9): 2823–30. PMC 182626 . PMID 12936980. doi:10.1128/AAC.47.9.2823-2830.2003.
