氟胺酮

化合物

氟胺酮2-氟脫氯氯胺酮2-FDCK)是一種解離麻醉藥[1]氯胺酮結構相似,在一些國家作為狡詐家藥物出售。[2][3][4]

氟胺酮
法律規範狀態
法律規範
  • Schedule I
  • NpSG
  • Class B
  • Illegal in Italy, Japan, Latvia, Singapore, Sweden and Switzerland
識別資訊
  • 2-(2-Fluorophenyl)-2-methylamino-cyclohexanone
CAS號111982-50-4  checkY
PubChem CID
ChemSpider
UNII
CompTox Dashboard英語CompTox Chemicals Dashboard (EPA)
化學資訊
化學式C13H16FNO
摩爾質量221.28 g·mol−1
3D模型(JSmol英語JSmol
  • CNC1(CCCCC1=O)c2ccccc2F
  • InChI=1S/C13H16FNO/c1-15-13(9-5-4-8-12(13)16)10-6-2-3-7-11(10)14/h2-3,6-7,15H,4-5,8-9H2,1H3
  • Key:PHFAGYYTDLITTB-UHFFFAOYSA-N

管制信息

編輯

氟胺酮在義大利、[5]日本、[6]拉脫維亞、[7]新加坡、[8]瑞典[9]、瑞士[10]和中國[11]是非法物質;在加拿大、[12]比利時[13]和英國[14]被全面禁止。


參考文獻

編輯
  1. ^ Moghimi A, Rahmani S, Zare R, Sadeghzadeh M. Synthesis of 2-(2-Fluorophenyl)-2-methylamino-Cyclohexanone as a New Ketamine Derivative. Synthetic Communications. 2014-07-18, 44 (14): 2021–2028 [2023-02-21]. S2CID 98475552. doi:10.1080/00397911.2014.885053. (原始內容存檔於2023-02-21) (英語). 
  2. ^ Davidsen AB, Mardal M, Holm NB, Andreasen AK, Johansen SS, Noble C, et al. Ketamine analogues: Comparative toxicokinetic in vitro-in vivo extrapolation and quantification of 2-fluorodeschloroketamine in forensic blood and hair samples. Journal of Pharmaceutical and Biomedical Analysis. February 2020, 180: 113049. PMID 31881397. S2CID 209499229. doi:10.1016/j.jpba.2019.113049. 
  3. ^ Wang PF, Neiner A, Lane TR, Zorn KM, Ekins S, Kharasch ED. Halogen Substitution Influences Ketamine Metabolism by Cytochrome P450 2B6: In Vitro and Computational Approaches. Molecular Pharmaceutics. February 2019, 16 (2): 898–906. PMC 9121441 . PMID 30589555. doi:10.1021/acs.molpharmaceut.8b01214. 
  4. ^ Tang MH, Li TC, Lai CK, Chong YK, Ching CK, Mak TW. Emergence of new psychoactive substance 2-fluorodeschloroketamine: Toxicology and urinary analysis in a cluster of patients exposed to ketamine and multiple analogues. Forensic Science International. July 2020, 312: 110327. PMID 32460225. S2CID 218954528. doi:10.1016/j.forsciint.2020.110327. 
  5. ^ Article 1. Aggiornamento delle tabelle contenenti l'indicazione delle sostanze stupefacenti e psicotrope, di cui al decreto del Presidente della Repubblica 9 ottobre 1990, n. 309 e successive modificazioni ed integrazioni. Inserimento nella tabella I e nella tabella IV di nuove sostanze psicoattive. 13 March 2020 [2023-02-21]. (原始內容存檔於2022-11-16) (Italian). 
  6. ^ "指定薬物一覧" (PDF) (in Japanese). Ministry of Health, Labour and Welfare
  7. ^ Noteikumi par Latvijā kontrolējamajām narkotiskajām vielām, psihotropajām vielām un prekursoriem. Latvijas Republikas tiesību akti. [2023-02-21]. (原始內容存檔於2023-02-21) (Latvian). 
  8. ^ Misuse of Drugs Act – Singapore Statutes Online. sso.agc.gov.sg. [2023-02-21]. (原始內容存檔於2021-04-17). 
  9. ^ Förordning (1999:58) om förbud mot vissa hälsofarliga varor Svensk författningssamling 1999:1999:58 t.o.m. SFS 2019:631 – Riksdagen. Riksdagsförvaltningen. www.riksdagen.se. [2023-02-21]. (原始內容存檔於2023-02-21) (Swedish). 
  10. ^ Verordnung des EDI über die Verzeichnisse der Betäubungsmittel, psychotropen Stoffe, Vorläuferstoffe und Hilfschemikalien. Der Bundesrat. [2023-02-21]. (原始內容存檔於2023-04-27) (German). 
  11. ^ 关于将合成大麻素类物质和氟胺酮等18种物质列入《非药用类麻醉药品和精神药品管制品种增补目录》的公告 (PDF). 中華人民共和國公安部. 2021-05-12 (中文(中國大陸)). 
  12. ^ Controlled Drugs and Substances Act (S.C. 1996, c. 19). March 18, 2021 [2023-02-21]. (原始內容存檔於2022-04-08). 
  13. ^ de Schutter A, Evenepoel T, Schrooten J. Dossier Nieuwe Psychoactieve Stoffen. Brussel: VAD. 2019 [2023-02-21]. (原始內容存檔於2023-05-25). 
  14. ^ Misuse of Drugs Act 1971. [7 March 2021]. (原始內容存檔於2023-03-09).