補體成分6

補體成分C6（Complement component 6），在人體內是一個由C6基因編碼的蛋白質，是補體系統的一部分，功能是形成膜攻擊複合物（MAC）。C6缺陷的患者更易被細菌感染。

補體成分6
已知的結構 PDB 直系同源搜尋: PDBe RCSB PDBID列表 3T5O、​4A5W、​4E0S
識別號
別名	C6；, complement C6
外部ID	OMIM：217050 MGI：88233 HomoloGene：47 GeneCards：C6
相關疾病
complement component 9 deficiency
基因位置（人類） 染色體 5號染色體 基因座 5p13.1 起始 41,142,116 bp 終止 41,261,438 bp
基因位置（小鼠） 染色體 小鼠15號染色體 基因座 15 A1|15 1.97 cM 起始 4,756,657 bp 終止 4,844,449 bp
基因本體 分子功能 • 血漿蛋白結合 細胞組分 • 細胞外區域 • 外排體 • 補體系統膜攻擊複合物 生物學過程 • positive regulation of activation of membrane attack complex • immune system process • complement activation • in utero embryonic development • 細胞溶解 • regulation of complement activation • 免疫反應 • positive regulation of angiogenesis • 經典途徑 • positive regulation of complement activation • 先天免疫系統 Sources:Amigo / QuickGO
直系同源
物種	人類	小鼠
Entrez	729	12274
Ensembl	ENSG00000039537	ENSMUSG00000022181
UniProt	P13671	無資料
mRNA​序列	NM_000065 ​NM_001115131	NM_016704
蛋白序列	NP_000056 ​NP_001108603	無資料
基因位置​（UCSC）	Chr 5: 41.14 – 41.26 Mb	Chr 15: 4.76 – 4.84 Mb
PubMed​查找
維基資料
檢視/編輯人類 檢視/編輯小鼠

拓展閱讀

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外部連結

• 醫學主題詞表（MeSH）：Complement+C6