SCH-5472

化合物

SCH-5472是一種含氮有機化合物,分子式C19H23NO,能作為興奮劑[1],1950年代由先靈葆雅開發[2]

SCH-5472
識別資訊
  • 2-benzhydryl-1-methyl-piperidin-3-ol
CAS號20068-90-0((phenylsuccinate))  checkY
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化學資訊
化學式C19H23NO
摩爾質量281.40 g·mol−1
3D模型(JSmol英語JSmol
  • OC(CCCN1C)C1C(C2=CC=CC=C2)C3=CC=CC=C3
  • InChI=1S/C19H23NO/c1-20-14-8-13-17(21)19(20)18(15-9-4-2-5-10-15)16-11-6-3-7-12-16/h2-7,9-12,17-19,21H,8,13-14H2,1H3 ☒N
  • Key:DQNBDZSLMWHFTB-UHFFFAOYSA-N ☒N
合成方式[3]

參考文獻

編輯
  1. ^ Nodine JH, Bodi T, Slap J, Levy HA, Siegler PE. Preliminary trial of a new stimulant SCH 5472 in ambulatory patients with depression, exhaustion, or hypersomnia syndrome. Antibiotic Medicine & Clinical Therapy. December 1960, 7: 771–6. PMID 13729397. 
  2. ^ US patent 2997478,Walter LA, Sperber N,「Oxygenated Piperidines and Process for their Manufacture」,發行於1961-08-22,指定於Schering 
  3. ^ Walter, L., Springer, C., Kenney, J., Galen, S., & Sperber, N. (1968). Derivatives of 3-Piperidinol as Central Stimulants. Journal of Medicinal Chemistry, 11(4), 792–796. https://doi.org/10.1021/jm00310a612