細胞色素c
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細胞色素複合體(英語:cytochrome complex)簡稱 細胞色素c(cyt c),是一種血红素蛋白(hemoprotein),屬於“细胞色素c家族”[1]。細胞色素c會與粒線體內膜輕微連接,結構鬆散而微小的它和其他細胞色素不同,是一種高度可溶性蛋白,在水中的可溶性達每公升100克。細胞色素c是電子傳遞鏈不可或缺的元件,負責攜帶一粒電子,在複合物III和複合物IV之間傳遞。此外,它能夠接受氧化和還原反應,但不與氧結合。在人體中,細胞色素c已經由CYCS基因完成編碼[2][3]。
細胞色素c,體細胞 | |||||||||||||
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![]() 血紅素及細胞色素c | |||||||||||||
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标识 | |||||||||||||
代号 | CYCS; HCS; CYC | ||||||||||||
扩展标识 | 遗传学:123970 鼠基因:88578 同源基因:68675 GeneCards: CYCS Gene | ||||||||||||
RNA表达模式 | |||||||||||||
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更多表达数据 | |||||||||||||
直系同源体 | |||||||||||||
物种 | 人类 | 小鼠 | |||||||||||
Entrez | 54205 | 13063 | |||||||||||
Ensembl | ENSG00000172115 | n/a | |||||||||||
UniProt | P99999 | n/a | |||||||||||
mRNA序列 | NM_018947 | XM_975140 | |||||||||||
蛋白序列 | NP_061820 | XP_980234 | |||||||||||
基因位置 |
Chr 7: 25.12 – 25.13 Mb | n/a | |||||||||||
PubMed查询 | [1] | [2] | |||||||||||
交互作用
编辑參考資料
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- ^ Entrez Gene: cytochrome c. NCBI. 2011-06-18. (原始内容存档于2020-05-28) (英语).
- ^ Marco Tafani, Natalie O. Karpinich, Kathryn A. Hurster, John G. Pastorino, Timothy Schneider, Matteo A. Russo, John L. Farber. Cytochrome c release upon Fas receptor activation depends on translocation of full-length bid and the induction of the mitochondrial permeability transition. The Journal of Biological Chemistry. 2002-03-22, 277 (12): 10073–10082 [2019-05-25]. ISSN 0021-9258. PMID 11790791. doi:10.1074/jbc.M111350200. (原始内容存档于2019-10-13).
- ^ 新世紀生命科學課程改進計畫:神經生物學 第一章. 國立陽明大學生命科學院. [2011-07-02]. (原始内容存档于2012-01-10).
- ^ Michel, B; Bosshard H R. Spectroscopic analysis of the interaction between cytochrome c and cytochrome c oxidase. J. Biol. Chem. (UNITED STATES). Aug 1984, 259 (16): 10085–91. ISSN 0021-9258. PMID 6088481 (英语).
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- ^ Lynch, S R; Sherman D; Copeland R A. Cytochrome c binding affects the conformation of cytochrome a in cytochrome c oxidase. J. Biol. Chem. (UNITED STATES). Jan 1992, 267 (1): 298–302. ISSN 0021-9258. PMID 1309738 (英语).
延伸閱讀
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其他圖像
编辑-
ETC
外部連結
编辑- 細胞色素c蛋白 (页面存档备份,存于互联网档案馆)(英文)
- 細胞凋亡 & Caspase-3 蛋白酶 (页面存档备份,存于互联网档案馆) - PMAP 蛋白酶動畫(英文)* Template:UMichOPM - Calculated orientations of cytochromes c in the lipid bilayer
- 醫學主題詞表(MeSH):Cytochrome+c(英文)