6-MAPB6-(N-甲基-2-氨丙基)苯并呋喃,英語:6-(N-methyl-2-aminopropyl)benzofuran)是一种含氮有机化合物,化学式C12H15NO,是6-APBMDMA结构类似物,能作为精神药物[1][2][3][4]

6-MAPB
法律規範狀態
法律規範
识别信息
  • 1-(Benzofuran-6-yl)-N-methylpropan-2-amine
CAS号1354631-79-0  checkY
PubChem CID
ChemSpider
UNII
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C12H15NO
摩尔质量189.26 g·mol−1
3D模型(JSmol英语JSmol
  • CC(NC)CC1=CC(OC=C2)=C2C=C1
  • InChI=1S/C12H15NO/c1-9(13-2)7-10-3-4-11-5-6-14-12(11)8-10/h3-6,8-9,13H,7H2,1-2H3
  • Key:QLAAURQYEAEHBO-UHFFFAOYSA-N

参考文献

编辑
  1. ^ Welter J, Brandt SD, Kavanagh P, Meyer MR, Maurer HH. Metabolic fate, mass spectral fragmentation, detectability, and differentiation in urine of the benzofuran designer drugs 6-APB and 6-MAPB in comparison to their 5-isomers using GC-MS and LC-(HR)-MS(n) techniques (PDF). Analytical and Bioanalytical Chemistry. May 2015, 407 (12): 3457–3470. PMID 25711990. S2CID 5475974. doi:10.1007/s00216-015-8552-2. 
  2. ^ Welter-Luedeke J, Maurer HH. New Psychoactive Substances: Chemistry, Pharmacology, Metabolism, and Detectability of Amphetamine Derivatives With Modified Ring Systems. Therapeutic Drug Monitoring. February 2016, 38 (1): 4–11. PMID 26327309. S2CID 20737913. doi:10.1097/FTD.0000000000000240. 
  3. ^ Shimshoni JA, Winkler I, Golan E, Nutt D. Neurochemical binding profiles of novel indole and benzofuran MDMA analogues. Naunyn-Schmiedeberg's Archives of Pharmacology. January 2017, 390 (1): 15–24. PMID 27650729. S2CID 253741131. doi:10.1007/s00210-016-1297-4. hdl:10044/1/43622 . 
  4. ^ Brandt SD, Walters HM, Partilla JS, Blough BE, Kavanagh PV, Baumann MH. The psychoactive aminoalkylbenzofuran derivatives, 5-APB and 6-APB, mimic the effects of 3,4-methylenedioxyamphetamine (MDA) on monoamine transmission in male rats. Psychopharmacology. December 2020, 237 (12): 3703–3714. PMC 7686291 . PMID 32875347. doi:10.1007/s00213-020-05648-z.