氧雄龙
化合物
氧雄龙(英语:Oxandrolone)是一种雄激素和同化类固醇(AAS)药物,具有增重效应,能减缓皮质类固醇造成的异化作用[4],分子式C19H30O3。
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临床资料 | |
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商品名 | Oxandrin, Anavar, others |
其他名称 | Var; CB-8075; NSC-67068; SC-11585; Protivar; 17α-Methyl-2-oxa-4,5α-dihydrotestosterone; 17α-Methyl-2-oxa-DHT; 17α-Methyl-2-oxa-5α-androstan-17β-ol-3-one |
AHFS/Drugs.com | Monograph |
MedlinePlus | a604024 |
怀孕分级 |
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给药途径 | By mouth |
药物类别 | Androgen; Anabolic steroid |
ATC码 | |
法律规范状态 | |
法律规范 |
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药物动力学数据 | |
生物利用度 | 97%[1] |
血浆蛋白结合率 | 94–97%[1] |
药物代谢 | Kidneys (primarily), liver[3][1] |
生物半衰期 | Adults: 9.4–10.4 hours[1][2] Elderly: 13.3 hours[2] |
排泄途径 | Urine: 28% (unchanged)[2] Feces: 3%[2] |
识别信息 | |
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CAS号 | 53-39-4 ![]() |
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DrugBank | |
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KEGG | |
ChEBI | |
ChEMBL | |
CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.000.158 |
化学信息 | |
化学式 | C19H30O3 |
摩尔质量 | 306.45 g·mol−1 |
3D模型(JSmol) | |
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参考文献
编辑- ^ 1.0 1.1 1.2 1.3 Ashraf Mozayani; Lionel Raymon. Handbook of Drug Interactions: A Clinical and Forensic Guide. Springer Science & Business Media. 15 October 2003: 513– [2021-07-25]. ISBN 978-1-59259-654-6. (原始内容存档于2019-12-15).
- ^ 2.0 2.1 2.2 2.3 Miller JT, Btaiche IF. Oxandrolone treatment in adults with severe thermal injury (PDF). Pharmacotherapy. February 2009, 29 (2): 213–26 [2021-07-25]. PMID 19170590. S2CID 25780591. doi:10.1592/phco.29.2.213. hdl:2027.42/90285 . (原始内容存档 (PDF)于2021-08-29).
- ^ R.A.S Hemat. Andropathy. Urotext. 2 March 2003: 108– [2021-07-25]. ISBN 978-1-903737-08-8. (原始内容存档于2021-07-25).
- ^ William Llewellyn. Anabolics. Molecular Nutrition Llc. 2011: 342–352 [2021-07-25]. ISBN 978-0-9828280-1-4. (原始内容存档于2021-07-25).
外部链接
编辑- Oxandrin Homepage, savientpharma.com (via archive.org)
- Oxandrin Label (页面存档备份,存于互联网档案馆), fda.gov (retrieved 23 October 2009)
- Oxandrolone Side Effects, Interactions and Information. drugs.com. [2021-07-25]. (原始内容存档于2018-02-10).