胍那佐啶

化合物

胍那佐啶(英语:Guanazodine)是一种有机化合物,化学式为C9H20N4。它是一种降压交感神经抑制剂,其毒性和副作用比胍乙啶苄二甲胍弱。[1]

胍那佐啶
Skeletal formula of guanazodine
Ball-and-stick model of the guanazodine molecule
临床资料
ATC码
识别信息
  • 2-(Azocan-2-ylmethyl)guanidine
CAS号32059-15-7  checkY
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C9H20N4
摩尔质量184.29 g·mol−1
3D模型(JSmol英语JSmol
  • C1CCCNC(CC1)CNC(=N)N
  • InChI=1S/C9H20N4/c10-9(11)13-7-8-5-3-1-2-4-6-12-8/h8,12H,1-7H2,(H4,10,11,13)
  • Key:ZCVAIGPGEINFCX-UHFFFAOYSA-N

它可以通过2-硝基亚甲基-1-氮杂环庚烷的还原反应制得。[2]

参考文献

编辑
  1. ^ Shimizu, Takeshi; Hamakawa, Hiroshi; Tozuka, Tetsuo; Ohno, Hiroshi. Hypotensive effects of [(octahydro-2-azocinyl)methyl]guanidine (guanazodine). Nippon Yakurigaku Zasshi (1976), 72(7), 837-850.
  2. ^ Rakoczi, Jozsef; Beck, Ivan; Kiss, Csaba; Horvath, Imre; Nemes, Miklos. 2-Guanidinomethylperhydroazocine sulfate, 1976. DE2608186.