胍那佐啶

化合物

胍那佐啶(英語:Guanazodine)是一種有機化合物,化學式為C9H20N4。它是一種降壓交感神經抑制劑,其毒性和副作用比胍乙啶苄二甲胍弱。[1]

胍那佐啶
Skeletal formula of guanazodine
Ball-and-stick model of the guanazodine molecule
臨床資料
ATC碼
識別資訊
  • 2-(Azocan-2-ylmethyl)guanidine
CAS號32059-15-7  checkY
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard英語CompTox Chemicals Dashboard (EPA)
化學資訊
化學式C9H20N4
摩爾質量184.29 g·mol−1
3D模型(JSmol英語JSmol
  • C1CCCNC(CC1)CNC(=N)N
  • InChI=1S/C9H20N4/c10-9(11)13-7-8-5-3-1-2-4-6-12-8/h8,12H,1-7H2,(H4,10,11,13)
  • Key:ZCVAIGPGEINFCX-UHFFFAOYSA-N

它可以通過2-硝基亞甲基-1-氮雜環庚烷的還原反應製得。[2]

參考文獻

編輯
  1. ^ Shimizu, Takeshi; Hamakawa, Hiroshi; Tozuka, Tetsuo; Ohno, Hiroshi. Hypotensive effects of [(octahydro-2-azocinyl)methyl]guanidine (guanazodine). Nippon Yakurigaku Zasshi (1976), 72(7), 837-850.
  2. ^ Rakoczi, Jozsef; Beck, Ivan; Kiss, Csaba; Horvath, Imre; Nemes, Miklos. 2-Guanidinomethylperhydroazocine sulfate, 1976. DE2608186.