5α-双氢诺龙

5α-双氢诺龙
临床资料
其他名称	Dihydronandrolone; DHN; 5α-DHN; 5α-Dihydro-19-nortestosterone; 5α-Estran-17β-ol-3-one; 19-nor-5α-androstan-17β-ol-3-one
识别信息
	IUPAC命名法 (5S,8R,9R,10S,13S,14S,17S)-17-Hydroxy-13-methyl-2,4,5,6,7,8,9,10,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-one; ;
CAS号	1434-85-1
PubChem CID	94202;
ChemSpider	85015;
UNII	I0V6O3097Q;
ChEMBL	ChEMBL3137999;
CompTox Dashboard（英语：CompTox Chemicals Dashboard） (EPA)	DTXSID60931866 ;
化学信息
化学式	C18H28O2
摩尔质量	276.42 g·mol−1
3D模型（JSmol（英语：JSmol））	交互式图像;
熔点	130—131 °C（266—268 °F）
	SMILES C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CC[C@@H]4[C@@H]3CCC(=O)C4;
	InChI InChI=1S/C18H28O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h11,13-17,20H,2-10H2,1H3/t11-,13-,14+,15+,16-,17-,18-/m0/s1; Key:RHVBIEJVJWNXBU-PNOKGRBDSA-N;

5α-双氢诺龙（英语：5α-Dihydronandrolone，缩写5α-DHN、DHN）也被称为5α-双氢-19-去甲睾酮（5α-dihydro-19-nortestosterone）或5α-雌烷-17β-醇-3-酮（5α-estran-17β-ol-3-one）是一种天然同化类固醇（AAS）和诺龙（19-去甲睾酮）的5α还原衍生物^[2]，和5α还原酶催化睾酮生成5α-双氢睾酮（DHT）类似，5α还原酶也可催化19-去甲睾酮生成5α-双氢诺龙^[2]^[3]。

参考文献

^ A. Bowers, H. J. Ringold, E. Denot. Steroids. CI. 1 19-Nordihydrotestosterone Derivatives 2. Journal of the American Chemical Society. 1958-11, 80 (22): 6115–6118 [2021-01-21]. ISSN 0002-7863. doi:10.1021/ja01555a054 （英语）.
^ ^2.0 ^2.1 Kicman AT. Pharmacology of anabolic steroids. British Journal of Pharmacology. June 2008, 154 (3): 502–21. PMC 2439524  . PMID 18500378. doi:10.1038/bjp.2008.165.
^ John A. Thomas. Drugs, Athletes, and Physical Performance. Springer Science & Business Media. 6 December 2012: 29–. ISBN 978-1-4684-5499-4.

[1] A. Bowers, H. J. Ringold, E. Denot. Steroids. CI. 1 19-Nordihydrotestosterone Derivatives 2. Journal of the American Chemical Society. 1958-11, 80 (22): 6115–6118 [2021-01-21]. ISSN 0002-7863. doi:10.1021/ja01555a054 （英语）.

[Kicman2008-2] 2.0 ^2.1 Kicman AT. Pharmacology of anabolic steroids. British Journal of Pharmacology. June 2008, 154 (3): 502–21. PMC 2439524  . PMID 18500378. doi:10.1038/bjp.2008.165.

[Thomas2012-3] John A. Thomas. Drugs, Athletes, and Physical Performance. Springer Science & Business Media. 6 December 2012: 29–. ISBN 978-1-4684-5499-4.

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