IL2RB
位於22號人類染色體的基因
白介素-2受体β亚基(Interleukin-2 receptor subunit beta,缩写IL2RB)也称为“白介素-15受体β亚基”(IL15RB)、P70-75、分化簇122(CD122,cluster of differentiation 122)是一种细胞表面蛋白质,由人类基因 IL2RB 编码[7],能与白介素-2受体α亚基(CD25)、γ亚基(CD132)共同组成白介素-2受体[8],或与白介素-15受体α亚基(CD215)、γ亚基(CD132)共同组成白介素-15受体[9]。
参考资料
编辑- ^ 與IL2RB相關的疾病;在維基數據上查看/編輯參考.
- ^ 對Interleukin 2 receptor subunit beta起作用的藥物;在維基數據上查看/編輯參考.
- ^ 3.0 3.1 3.2 GRCh38: Ensembl release 89: ENSG00000100385 - Ensembl, May 2017
- ^ 4.0 4.1 4.2 GRCm38: Ensembl release 89: ENSMUSG00000068227 - Ensembl, May 2017
- ^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Entrez Gene: IL2RB interleukin 2 receptor, beta.
- ^ Zhou P. Emerging mechanisms and applications of low-dose IL-2 therapy in autoimmunity. Cytokine & Growth Factor Reviews. October 2022, 67: 80–88. PMID 35803833. S2CID 250200065. doi:10.1016/j.cytogfr.2022.06.003.
- ^ Anderson DM, Kumaki S, Ahdieh M, Bertles J, Tometsko M, Loomis A, Giri J, Copeland NG, Gilbert DJ, Jenkins NA. Functional characterization of the human interleukin-15 receptor alpha chain and close linkage of IL15RA and IL2RA genes. J. Biol. Chem. 1995, 270 (50): 29862–9. PMID 8530383. doi:10.1074/jbc.270.50.29862 .
外部链接
编辑