CYP27C1

CYP27C1
識別號
別名	CYP27C1；, cytochrome P450 family 27 subfamily C member 1
外部ID	HomoloGene：70240 GeneCards：CYP27C1
基因位置（人類）
染色體	2號染色體
終止	127,220,313 bp
基因本體
分子功能	• iron ion binding; • oxidoreductase activity; • heme binding; • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; • 金屬離子結合; • monooxygenase activity; • retinoic acid binding; • 11-cis retinal binding; • all-trans retinal binding; • all-trans-retinol binding; • all-trans retinol 3,4-desaturase activity; • all-trans retinal 3,4-desaturase activity; • all-trans retinoic acid 3,4-desaturase activity; • 11-cis-retinal 3,4-desaturase activity;
細胞組分	• 膜; • 細胞組件; • 細胞內膜結合細胞器;
生物學過程	• retinol metabolic process; • retinoic acid metabolic process; • retinal metabolic process;
	Sources:Amigo / QuickGO
直系同源
	339761
	無數據
	ENSG00000186684
	無數據
	Q4G0S4
	無數據
	NM_001001665; NM_001367501; NM_001367502
	無數據
	NP_001001665; NP_001354430; NP_001354431
	無數據
	維基數據
檢視/編輯人類

細胞色素 P450 27C1（英語：Cytochrome P450 27C1，縮寫CYP27C1）是細胞色素P450超家族的一員，由CYP27C1基因編碼，是定位於許多不同組織線粒體內膜的單加氧酶^[3]^[4]。CYP27C1在體內的主要功能是將視黃醇（維生素A1）轉化為維生素A2^[5]，此外還能催化多種反應，如膽固醇、甾體激素的合成與代謝^[6]。

參考文獻

^ ^1.0 ^1.1 ^1.2 GRCh38: Ensembl release 89: ENSG00000186684 - Ensembl, May 2017
^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Ota T, Suzuki Y, Nishikawa T, et al. Complete sequencing and characterization of 21,243 full-length human cDNAs. Nat. Genet. January 2004, 36 (1): 40–5. PMID 14702039. doi:10.1038/ng1285  .
^ Gerhard DS, Wagner L, Feingold EA, et al. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. October 2004, 14 (10B): 2121–7. PMC 528928  . PMID 15489334. doi:10.1101/gr.2596504.
^ Kramlinger, VM; Nagy, LD; Fujiwara, R; Johnson, KM; Phan, TT; Xiao, Y; Enright, JM; Toomey, MB; Corbo, JC; Guengerich, FP. Human cytochrome P450 27C1 catalyzes 3,4-desaturation of retinoids.. FEBS letters. 2016-05, 590 (9): 1304–12. PMID 27059013. doi:10.1002/1873-3468.12167.
^ Entrez Gene: CYP39A1. （原始內容存檔於2010-12-05）.