SNAPC2

小核RNA激活蛋白複合體，多肽2，45千道爾頓
Small nuclear RNA activating complex, polypeptide 2, 45kDa
小核RNA激活蛋白複合體，多肽2，45千道爾頓; Small nuclear RNA activating complex, polypeptide 2, 45kDa
標識
代號	SNAPC2; PTFDELTA; SNAP45
擴展標識	遺傳學：605076 鼠基因：1914861 同源基因：2318 GeneCards: SNAPC2 Gene
基因本體論描述
分子功能	· sequence-specific DNA binding transcription factor activity;
細胞成分	· nucleus; · nucleoplasm;
生物過程	· transcription from RNA polymerase II promoter; · transcription from RNA polymerase III promoter; · snRNA transcription; · gene expression;
	Sources: Amigo / QuickGO
RNA表達模式
	更多表達數據
直系同源體
物種	人類
Entrez	6618
Ensembl	ENSG00000104976
UniProt	Q13487
mRNA序列	NM_003083
蛋白序列	NP_003074
基因位置	Chr 19:; 7.99 – 7.99 Mb
PubMed查詢	[1]
	閱; 論; 編;

snRNA激活蛋白複合體第二亞基（英語：snRNA-activating protein complex subunit 2）是一個由人類基因SNAPC2編碼的蛋白質^[1]^[2]。

相互作用

SNAPC2會與SNAPC4^[3]^[4]相互作用。

參考文獻

^ Sadowski CL, Henry RW, Kobayashi R, Hernandez N. The SNAP45 subunit of the small nuclear RNA (snRNA) activating protein complex is required for RNA polymerase II and III snRNA gene transcription and interacts with the TATA box binding protein. Proc Natl Acad Sci U S A. July 1996, 93 (9): 4289–93. PMC 39528  . PMID 8633057. doi:10.1073/pnas.93.9.4289.
^ Entrez Gene: SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa.
^ Wong, M W; Henry R W, Ma B, Kobayashi R, Klages N, Matthias P, Strubin M, Hernandez N. The Large Subunit of Basal Transcription Factor SNAPc Is a Myb Domain Protein That Interacts with Oct-1. Mol. Cell. Biol. (UNITED STATES). January 1998, 18 (1): 368–77. ISSN 0270-7306. PMC 121507  . PMID 9418884.
^ Ma, B; Hernandez N. A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc. J. Biol. Chem. (United States). February 2001, 276 (7): 5027–35. ISSN 0021-9258. PMID 11056176. doi:10.1074/jbc.M009301200.

延伸閱讀

Henry RW, Sadowski CL, Kobayashi R, Hernandez N. A TBP-TAF complex required for transcription of human snRNA genes by RNA polymerase II and III. Nature. 1995, 374 (6523): 653–6. PMID 7715707. doi:10.1038/374653a0.
Maruyama K, Sugano S. Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. Gene. 1994, 138 (1–2): 171–4. PMID 8125298. doi:10.1016/0378-1119(94)90802-8.
Yoon JB, Roeder RG. Cloning of two proximal sequence element-binding transcription factor subunits (gamma and delta) that are required for transcription of small nuclear RNA genes by RNA polymerases II and III and interact with the TATA-binding protein. Mol. Cell. Biol. Advances in Molecular and Cell Biology. 1996, 16 (1): 1–9. ISBN 978-0-7623-0143-0. PMC 230972  . PMID 8524284. doi:10.1016/S1569-2558(08)60061-2.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K; et al. Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. Gene. 1997, 200 (1–2): 149–56. PMID 9373149. doi:10.1016/S0378-1119(97)00411-3.
Wong MW, Henry RW, Ma B; et al. The Large Subunit of Basal Transcription Factor SNAPc Is a Myb Domain Protein That Interacts with Oct-1. Mol. Cell. Biol. 1998, 18 (1): 368–77. PMC 121507  . PMID 9418884.
Ma B, Hernandez N. A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc. J. Biol. Chem. 2001, 276 (7): 5027–35. PMID 11056176. doi:10.1074/jbc.M009301200.
Acierno JS, Kennedy JC, Falardeau JL; et al. A physical and transcript map of the MCOLN1 gene region on human chromosome 19p13.3-p13.2. Genomics. 2001, 73 (2): 203–10. PMID 11318610. doi:10.1006/geno.2001.6526.
Strausberg RL, Feingold EA, Grouse LH; et al. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. 2003, 99 (26): 16899–903. PMC 139241  . PMID 12477932. doi:10.1073/pnas.242603899.
Hinkley CS, Hirsch HA, Gu L; et al. The small nuclear RNA-activating protein 190 Myb DNA binding domain stimulates TATA box-binding protein-TATA box recognition. J. Biol. Chem. 2003, 278 (20): 18649–57. PMID 12621023. doi:10.1074/jbc.M204247200.
Gerhard DS, Wagner L, Feingold EA; et al. The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC). Genome Res. 2004, 14 (10B): 2121–7. PMC 528928  . PMID 15489334. doi:10.1101/gr.2596504.

[pmid8633057-1] Sadowski CL, Henry RW, Kobayashi R, Hernandez N. The SNAP45 subunit of the small nuclear RNA (snRNA) activating protein complex is required for RNA polymerase II and III snRNA gene transcription and interacts with the TATA box binding protein. Proc Natl Acad Sci U S A. July 1996, 93 (9): 4289–93. PMC 39528  . PMID 8633057. doi:10.1073/pnas.93.9.4289.

[entrez-2] Entrez Gene: SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa.

[pmid9418884-3] Wong, M W; Henry R W, Ma B, Kobayashi R, Klages N, Matthias P, Strubin M, Hernandez N. The Large Subunit of Basal Transcription Factor SNAPc Is a Myb Domain Protein That Interacts with Oct-1. Mol. Cell. Biol. (UNITED STATES). January 1998, 18 (1): 368–77. ISSN 0270-7306. PMC 121507  . PMID 9418884.

[pmid11056176-4] Ma, B; Hernandez N. A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc. J. Biol. Chem. (United States). February 2001, 276 (7): 5027–35. ISSN 0021-9258. PMID 11056176. doi:10.1074/jbc.M009301200.

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