MDAI5,6-亞甲二氧基-2-氨基茚滿,英語:5,6-methylenedioxy-2-aminoindane)是一種含氮有機化合物,分子式C10H11NO2,屬於2-氨基茚滿衍生物,1990年代由普渡大學的David E. Nichols團隊開發[2],結構與MDAT類似[3],能作為選擇性血清素釋放劑(SSRA)[4]

MDAI
臨床資料
其他名稱5,6-Methylenedioxy-2-aminoindane; 5,6-Methylenedioxy-2-aminoindan; Methylenedioxyaminoindane; Methylenedioxyaminoindan
給藥途徑口服給藥
藥物類別英語Drug classSerotonin–norepinephrine releasing agent; Entactogen
ATC碼
  • 未分配
法律規範狀態
法律規範
  • NpSG
  • PSA
  • Illegal in China
藥物動力學數據
作用時間2–6 小時
識別資訊
  • 6,7-Dihydro-5H-cyclopenta[f] [1,3]benzodioxol-6-amine
CAS號132741-81-2
PubChem CID
ChemSpider
UNII
ChEBI
ChEMBL
CompTox Dashboard英語CompTox Chemicals Dashboard (EPA)
化學資訊
化學式C10H11NO2
摩爾質量177.20 g·mol−1
3D模型(JSmol英語JSmol
  • C1C(CC2=CC3=C(C=C21)OCO3)N
  • InChI=1S/C10H11NO2/c11-8-1-6-3-9-10(13-5-12-9)4-7(6)2-8/h3-4,8H,1-2,5,11H2 checkY
  • Key:FQDRMHHCWZAXJM-UHFFFAOYSA-N checkY

參考文獻

編輯
  1. ^ Anvisa. RDC Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial [Collegiate Board Resolution No. 804 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control]. Diário Oficial da União. 2023-07-24 (2023-07-25) [2023-08-27]. (原始內容存檔於2023-08-27) (巴西葡萄牙語). 
  2. ^ Johnson MP, Conarty PF, Nichols DE. [3H]monoamine releasing and uptake inhibition properties of 3,4-methylenedioxymethamphetamine and p-chloroamphetamine analogues. European Journal of Pharmacology. July 1991, 200 (1): 9–16. PMID 1685125. doi:10.1016/0014-2999(91)90659-e. 
  3. ^ Pinterova N, Horsley RR, Palenicek T. Synthetic Aminoindanes: A Summary of Existing Knowledge. Frontiers in Psychiatry (Frontiers Media SA). 17 November 2017, 8: 236. PMC 5698283 . PMID 29204127. doi:10.3389/fpsyt.2017.00236 . 
  4. ^ Sainsbury PD, Kicman AT, Archer RP, King LA, Braithwaite RA. Aminoindanes--the next wave of 'legal highs'?. Drug Testing and Analysis (Wiley). 2011, 3 (7-8): 479–482. PMID 21748859. doi:10.1002/dta.318. 

外部連結

編輯