1,3,3,5,5-五甲基環己胺

化合物

1,3,3,5,5-五甲基環己胺(英語:1,3,3,5,5-pentamethylcyclohexanamine,或稱為Neramexane)是一種美金剛胺相關藥物,分子式為C11H23N[1],作為一種NMDA受體拮抗劑[2],具有神經保護作用[3]

1,3,3,5,5-五甲基環己胺
臨床資料
ATC碼
  • 未分配
識別資訊
  • 1,3,3,5,5-pentamethylcyclohexanamine
CAS號219810-59-0  checkY
PubChem CID
ChemSpider
UNII
CompTox Dashboard英語CompTox Chemicals Dashboard (EPA)
ECHA InfoCard100.107.752 編輯維基數據鏈接
化學資訊
化學式C11H23N
摩爾質量169.31 g·mol−1
3D模型(JSmol英語JSmol
  • CC1(CC(CC(C1)(C)N)(C)C)C
  • InChI=1S/C11H23N/c1-9(2)6-10(3,4)8-11(5,12)7-9/h6-8,12H2,1-5H3 ☒N
  • Key:OGZQTTHDGQBLBT-UHFFFAOYSA-N ☒N

參考文獻

編輯
  1. ^ Gilling K, Jatzke C, Wollenburg C, Vanejevs M, Kauss V, Jirgensons A, Parsons CG. A novel class of amino-alkylcyclohexanes as uncompetitive, fast, voltage-dependent, N-methyl-D-aspartate (NMDA) receptor antagonists--in vitro characterization. Journal of Neural Transmission. 2007, 114 (12): 1529–37. PMID 17728997. S2CID 8654883. doi:10.1007/s00702-007-0792-7. 
  2. ^ Danysz W, Parsons CG, Jirgensons A, Kauss V, Tillner J. Amino-alkyl-cyclohexanes as a novel class of uncompetitive NMDA receptor antagonists. Current Pharmaceutical Design. 2002, 8 (10): 835–43. PMID 11945134. doi:10.2174/1381612024607117. 
  3. ^ Danysz W, Parsons CG. Neuroprotective potential of ionotropic glutamate receptor antagonists. Neurotoxicity Research. March 2002, 4 (2): 119–26. PMID 12829411. S2CID 9413469. doi:10.1080/10298420290015872. 

外部連結

編輯